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Biomedical subjects

A S Frankel

Publications and source records attributed to A S Frankel.

5 recordsLinked to original sources

Rhabdomyolysis, renal failure and schizophrenia.

Rhabdomyolysis appears to be a complication that psychiatrists need to be aware of. A case is reported here of a patient who developed rhabdomyolysis and renal failure as a result of intense activity during a psychotic episode.

Acute Kidney Injury

Air embolism during posterior spinal fusion.

A 12-year-old healthy girl underwent a 13-level posterior spinal fusion with Harrington rod, Luque instrumentation and Drummond spinous process wires for scoliosis repair. Her anaesthetic induction and initial intraoperative course were completely uneventful until a precipitous blood pressure drop occurred accompanied by a significant decrease in heart rate. The Harrington rod was being manipulated at the same time as bone chips were being removed from the iliac crest. Although more common intraoperative events were presumed and treatment initiated, venous air embolism (VAE) was considered the aetiology of these events when a transient decrease in the end-tidal carbon dioxide (ETCO2) and an increase in the end-tidal nitrogen (ETN2) was noted by mass spectrometry. This transient episode resolved within a relatively narrow window of time, and the case proceeded without further incident, including a wake-up test, to the conclusion of surgery.

Child

Elimination of the sarcoma genome from murine sarcoma virus transformed cat cells.

Cat cells transformed by Moloney murine sarcoma virus contain virus-specific sequences in their RNA and DNA. Cloned, spontaneous revertant cell lines derived from clones of these cells had no evidence of the sarcoma genome in the cell RNA or DNA as judged by RNA-complementary DNA or DNA-complementary DNA hybridizations. ?This is apparently the first report of loss of a transforming genome in a revertant cell line.

Cell Line