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Biomedical subjects

A S Gasparov

Publications and source records attributed to A S Gasparov.

At least 19 recordsLinked to original sources
PubMed1993

[The effect of a decrease in body weight in patients with the polycystic ovary syndrome].

Eighty patients with the polycystic ovaries syndrome and excessive body mass were examined. In 60 patients body mass reduction resulted from diets and in 20 it occurred over the course of acupuncture. Such treatment resulted in pregnancy in 27 (33.7%) patients. Therefore, diets or acupuncture for body mass reduction are recommended for patients with polycystic ovaries and obesity as the first stage of treatment.

Acupuncture Therapy↗
PubMed1992

[Diagnostic and surgical laparoscopy in polycystic ovary syndrome].

A total of 202 patients with polycystic ovaries were involved in examination. The study has distinguished the laparoscopic signs of polycystic ovaries: smooth glossy tightly stretched surface of the ovaries with a characteristic vascular pattern or loops; the presence of subcapsular cysts. Ovarian section shows small cysts with transparent or yellowish contents. The histologic signs are thickening of the protein coating, increased count of primary, secondary and cystic atretic follicles (by 2-5 times) and a lowered level of tertiary follicles. Clinical and hormonal signs include disordered rhythm of the menstrual cycle, stable anovulation, a high (over 2) LH/FSH index, an elevated T level. Laparoscopic resection of the ovaries to make their size normal is a method of choice among this technique, standard or wide ovarian biopsy.

Adult↗
PubMed1990

[Results of laparoscopy in patients with polycystic ovary syndrome after surgical treatment].

Laparoscopic studies have been done in 42 patients after laparotomic ovarian wedge resection (group 1), 12 women after laparoscopic ovarian thermocauterization (group 2) and 24 patients after laparoscopic ovarian wedge resection (group 3). Prominent adhesions were found out in the pelvis in group 1 women and milder ones in group 2 patients. The incidence of adhesions was significantly lower in group 3. It suggests that wedge resection using laparoscopy represents a method of choice for surgical ovarian correction.

Adolescent↗
PubMed1990

[Effectiveness of infertility therapy in patients with hyperandrogenism].

170 patients of reproductive age with hyperandrogenemia and infertility were examined. 101 (59.4%) patients became pregnant after the complete therapy of infertility. The examination of patients after non-effective therapy stated that they had had more height stage of androgenemia and remarkable deviation in results of genetic observation in comparison with the same indications of the pregnant women.

Adult↗
PubMed1990

[Comparative study of the diagnostic value of hysterosalpingography and laparoscopy].

A total of 100 women had either hysterosalpingography with watersoluble Verografin or lipidsoluble Jodlipol for the assessment of tubal patency. Of these, all had laparoscopy. Laparoscopy have been shown to be the best test of tubal abnormalities. Hysterosalpingraphy with lipidsoluble contrast medium is poorly informative while the method of investigating the tubal pathology and cannot be used in clinical practice.

Adult↗
PubMed1990

[The polycystic ovary syndrome and increased body mass].

Eighty patients with the polycystic ovarys syndrome (PCOS) and excessive body weight were investigated. Weight loss was achieved by means of a diet in 60 patients, and acupuncture in 20 patients. This kind of treatment resulted in pregnancy in 27 (33.7%) patients. Therefore therapeutic diet or acupuncture may be recommended as the first stage of treatment for weight reduction in PCOS patients.

Adult↗
PubMed1990

[Androgenization in patients with polycystic ovary syndrome].

150 infertile patients with the polycystic ovary syndrome (PCOS), aged 19 to 36 years, have been investigated. PCOS was diagnosed on the basis of clinical symptoms, and the diagnosis was verified by laparoscopy, followed by histologic investigation of ovarian biopsy specimens. Hirsutism was found in 43% of the patients, while hair growth was marginal in 30% and normal in 27%. Testosterone (T) levels were increased significantly (p less than 0.05) in the PCOS patients with hirsutism or marginal hair growth, as compared to reference values.

Adult↗
PubMed1990

[Endoscopic surgery in the treatment of polycystic ovary syndrome].

202 patients with the polycystic ovary syndrome (PCOS) were investigated and divided into three groups depending on the variant of endoscopic surgical correction of polycystic ovaries. The highest conception rate (70.6%) was noted in group III; the ovaries of patients in this group were reduced to normal size as a result of dissection. We conclude that endoscopic resection of polycystic ovaries with reduction of ovarian size to normal limits may be considered a preferred variant of surgical treatment for PCOS.

Adult↗
PubMed1990

[Clinical and laboratory findings in patients with infertility and various forms of hyperandrogenism].

The study groups included 120 infertile females with hyperandrogenism: group I-47 patients with androgenic adrenal hyperfunction; group II-51 patients with androgenic adrenal and ovarian hyperfunction; group III-22 patients with androgenic ovarian hyperfunction. The patients with an adrenal pattern of hyperandrogenism demonstrated lower degrees of androgenization (lower hirsutism and clitorism) as well as a less pronounced impairment of the menstrual cycle versus the examinees from the other groups mentioned.

Abortion, Induced↗
PubMed1989

[Value of roentgenography of the bones of the skull vault and the sella turcica for the prognosis of the effectiveness of the treatment of infertility in patients with hyperandrogenia].

Thorough clinical and roentgenological examinations of the skull were conducted in 83 infertile patients with hyperandrogenism. The parameters of their health status evidenced various degrees of androgenism. The roentgenological picture of their skull and Turkish saddle was significantly different from the normal one. A small and round-shaped pattern of the Turkish saddle was significantly more often documented in the hyperandrogenic females whose infertility treatment was a failure. These prognostic criteria should be considered when the practicability of the treatment for this pattern of infertility is discussed.

Adult↗
PubMed1989

[Multiple correlation analysis of hormone parameters in sterile female patients with hyperandrogenism (correction of endometriosis)].

The authors examined 100 infertile women of reproductive age with various degrees of hyperandrogenism. As a result of multiple correlation analysis it was found that the state of hirsutism and the ratio of body weight to height are the most sensitive indicators of the testosterone action in reproductive age (r = + 0.56, p less than 0.1, r = + 0.60, p less than 0.05). There was no correlation between LH, FSH, PRLI, E2 T and K values. The assembled results suggest the variable character of factors which influence clinical manifestations of the disease and explain the heterogeneity of symptoms.

Adult↗
PubMed1989

[Characteristics of hirsutism in fertile Russian and Armenian women and in infertile patients].

The authors investigated the characteristic features of pubescence in healthy fertile women of Russian (n = 300) and Armenian nationality (n = 150) and in infertile patients (n = 300). They assessed the criteria or normal female pubescence, liminal pubescence and hirsutism in the two populations. In healthy Armenian women the criteria of normal female pubescence and hirsutism are more marked (p less than 0.001) than in Russian women. In Armenian women significantly more frequently (p less than 0.05) an increased sensitivity of the skin to testosterone was observed, as compared with Russian women. In infertile patients hirsutism was found in 20%.

Adult↗
PubMed1989

[Clinical manifestations of hyperandrogenism in infertile women].

The authors investigated clinical manifestations of hyperandrogenism in infertile women with hirsutism. Assessment of accurate quantitative indicators (hirsutic number, clitoral index, body mass growth coefficient and morphogram) made it possible to characterize the manifestations of hyperandrogenism in infertile women (n = 112). Correlation analysis revealed that the state of hirsutism and the body mass growth relations are the most sensitive indicators of the action of androgens (testosterone) in fertile age.

Adult↗
PubMed1989

[Clinico-dermatoglyphic correlations in patients with hyperandrogenia].

A clinical dermatoglyphic study of 100 infertile hyperandrogenic patients demonstrated signs of androgenization in all of those. Their dermatoglyphic parameters differed from normal. Hyperandrogenic patients with treatment-resistant infertility showed a higher degree of androgenization and more significant deviations of dermatoglyphic parameters, as compared to the patients whose treatment resulted in pregnancy. Dermatoglyphic characteristics should be taken into account in predicting the practicability of treatment in patients with infertility due to hyperandrogenism.

Adult↗