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Biomedical subjects

A S Hudspeth

Publications and source records attributed to A S Hudspeth.

At least 37 records · Page 2Linked to original sources

Malignant fibrous histiocytoma of the mediastinum and lung: a report of three cases.

One case of primary malignant fibrous histiocytoma of the lung and two cases of that tumor in the mediastinum are reported. Primary malignant fibrous histiocytoma is rare in those areas, appearing more commonly in deep fascia and skeletal muscles of the extremities and torso and in the retroperitoneum. Most of the tumors contain both fibroblast-like and histiocyte-like cells; some contain pleomorphic giant cells and inflammatory cells. They are often confused with other sarcomas, and their true biologic potential is not clearly defined. Radiation appears to be a very useful adjunct to surgical therapy and was used in the cases reported here.

Female↗

Clinical spectrum of blunt tracheobronchial disruption illustrated by seven cases.

Tracheobronchial disruption resulting from blunt trauma is unusual, but when it does occur it can have serious immediate and delayed consequences. A high index of suspicion for this injury and an awareness of the variety of clinical, radiographic, and bronchoscopic presentations are the key elements in diagnosis. Our experience with seven patients with blunt tracheobronchial trauma seen from 1972 through 1980 is reviewed. Emphasis is placed on the importance of early diagnosis to avoid the complications associated with delayed repair.

Accidents, Traffic↗

Circumflex coronary artery bypass grafting via transverse sinus.

Grafting the circumflex coronary artery has been more difficult technically than the right or anterior descending because of its posterior location and the angles of its marginal branches. However, grafting this artery has been substantially simplified by a method wherein the graft is passed directly through the transverse sinus and anastomosed to the back of the ascending aorta. This follows the most direct course to the ascending aorta and the graft is much shorter than one brought anterior to the heart. There is little chance of kinking the graft, since its angle of attachment is ideal, and due to the anatomical configuration of the transverse sinus, there is more room for the graft and compression is unlikely. This allows more room on the anterior surface of the aorta for grafts to other coronary arteries. This method has been used in 50 cases and blood flows have been excellent. Twelve of these cases have been restudied postoperatively and the grafts are patent.

Coronary Artery Bypass↗

De subitaneis mortibus. X. Familial congential heart block.

Complete heart block was found shortly after birth in a brother and sister (not twins). Both were treated by electronic pacing because of symptoms attributable to inadequate cardiac output and electrical instability of heart. The boy has done well with his artificial pacemaker and is now six years old. His sister died of complications due in part to the large size of her pacemaker and small size of her body. At necropsy special studies of her heart included the centers for normal impulse formation and concuction. The primary abnormalities were at the junction of atrial septum with atrioventricular (A-V) node, and at the origin of the two bundle branches from the His bundle. The A-V node was isolated by collagen at all its margins except its junction with the His bundle. The proximal His bundle was essentially normal, but from that point on through the initial protions of both the left and right bundle branches there was extensive caseous degeneration which interrupted any possible conduction. These findings are discussed in relation to fetal and postnatal development of the human A-V node, and the His bundle and its branches; and in the context of a recently observed mathematical relationship between sinus rate and two forms of experimentally produced A-V junctional escape rhythms.

Atrioventricular Node↗

Abdominal angina.

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Arteriosclerosis Obliterans↗