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Biomedical subjects

A S Ibrahim

Publications and source records attributed to A S Ibrahim.

49 records · Page 3Linked to original sources

Tamponade and injection sclerotherapy in the management of bleeding oesophageal varices.

One hundred patients with bleeding oesophageal varices were randomized into two treatment groups after resuscitation. One group was managed by tamponade only (group 1); the other group (group 2) was treated by endoscopic injection of oesophageal varices. The patients in group 2 were further subdivided into 25 patients (group 2a), who had tamponade applied immediately after sclerotherapy, and 25 patients (group 2b), who had sclerotherapy without subsequent tamponade. Injection of varices controlled the acute bleeding episode more effectively than tamponade (74 per cent in group 2 v. 42 per cent in group 1). There was no significant difference in the overall mortality rate of the two groups, but group 2 had a significantly higher proportion of Child's grade C patients (38/50 v. 29/50 = 76 v. 58 per cent). If only Child's grade C patients are considered, 16 out of 29 (55 per cent) died in group 1, whereas only 12 out of 38 (32 per cent) died in group 2 (P less than 0.05). Tamponade applied after sclerotherapy had no demonstrable effect on the outcome of sclerotherapy. The long term follow-up of patients (maximum 4 years) showed that recurrence of bleeding was less in the sclerotherapy group (8.1 per cent) than in the tamponade only group (27.6 per cent; P less than 0.05).

Adolescent↗

A study on the etiological factors of bilharzial bladder cancer in Egypt: 5-urinary nitrite in a rural population.

Urinary nitrite was present in 5.6% of 2379 individuals from a rural population infested with "Schistosoma haematobium". A higher frequency was observed in symptomatic patients with active bilharzial cystitis (25%) and patients with bladder cancer associated with schistosomiasis (66.2%); conversely, urinary nitrite was absent in normal urban individuals. The frequency of urinary nitrite was higher in females (6.4%) than males (4.6%), and was more frequent in adults than extremes of age. The presence of urinary nitrite was associated with urinary infection and was commonly accompanied by cellular atypia in urine, in the form of dysplasia. Under these circumstances, carcinogenic nitrosamines are liable to be produced in the bladder from urinary nitrite and amines. These observation support the possible role of urinary bacterial infection, commonly associated with bilharzial cystitis, in bladder carcinogenesis.

Adolescent↗

Prostatic carcinoma in Egypt: epidemiology and etiology.

In Egypt, the relative frequency of prostatic carcinoma is much lower than elsewhere reported. On the other hand, carcinoma of the male breast shows a strikingly higher frequency. These findings could be related to the prevalent bilharzial infestation which impairs the liver detoxication mechanism. As a result there is an increased estrogen and diminished androgen level. These metabolic changes can contribute to the rarity of prostatic cancer and the high frequency of breast cancer in males.

Adult↗

Dogmatism and related personality factors among Egyptian university students.

The Dogmatism Scale and 13 personality tests measuring authoritarianism, rigidity, neuroticism,and extremeness were administered to 250 male and female students at the University of Cairo, Egypt, to investigate whether there are any differences in dogmatism and its underlying personality characteristics associated with the Egyptian culture in comparison with the American and English cultures. The Egyptian mean dogmatism score was larger than the comparable means obtained for American and English college students (p less than .001). However, with use of Hotelling factor analysis and the varimax orthogonal rotation method, dogmatism was found to be almost independent of the rigidity and extremeness scores, indicating that in cultures where strength of believing can be considered a part of the socially accepted norms (e.g., Arab Eastern cultures), dogmatism rests on different cognitive and personality processes than in the West.

Adolescent↗

Protein content of thoracic duct lymph in patients with bilharzial hepatic fibrosis.

The proteins in the thoracic duct lymph were studied in 46 patients with bilharzial hepatic disease in various stages. The thoracic duct proteins were compared to those of serum and ascitic fluid. Total protein and albumin in thoracic duct lymph were 66 and 69% of the concentration of those in the serum of nonascitic patients. The proteins in the thoracic duct lymph were 29% of the serum level in patients with tense ascites. The lymph to serum and ascitic fluid to serum ratios of the total protein and albumin were similar to each other in moderate and severe ascites, reflecting a low protein content in both the ascitic fluid and thoracic duct lymph. The gamma-globulin concentration was raised in the serum of all patients as well as in the ascitic fluid of those with tense ascites. A contrasting pattern of the proteins is present in the thoracic duct lymph in bilharzial hepatic fibrosis. In the early stages the lymph has a relatively high concentration of protein, which decreases as the disease advances.

Adult↗

Long-term intermittent haemodialysis in Egypt.

The pattern of mortalities from genitourinary diseases in Egypt was analysed from recent official figures. On the basis of certain assumptions concerning etiology, age, and geographical distribution, it was estimated that 37.7 per million of the general population would benefit from regular dialysis treatment, though the facilities available will permit only 5% of these subjects to receive treatment in 1975. As other diseases and conditions are much more prevalent, no great relative increase in dialysis facilities in Egypt is anticipated in the near future. A computer-controlled plan is suggested for organizing regular dialysis treatment at the national level to ensure an appropriate choice of medically suitable subjects of highest value to the community. Means of reducing the need for dialysis by minimizing the incidence of terminal chronic renal failure and of making best use of the available facilities are discussed.

Adolescent↗

Cytologic detection of bladder cancer in a rural Egyptian population infected with schistosomiasis.

A study was initiated in September 1976 to detect early bladder carcinoma by selective cytologic screening in a rural Egyptian population infested with Schistosoma haematobium. All persons in a high-risk group, i.e., farmers aged 20 years and above, and selected persons from two low-risk groups were screened. Bladder carcinoma was detected in 11 patients among the 4,769 individuals screened in the high-risk group, for a yield of 2.3 per 1,000. No tumors were detected in the 3,975 individuals in the low-risk groups. Cytologically diagnosed tumors were verified by histology in all cases. One of the detected tumors in a female was found to be metastatic from carcinoma of the cervix. The primary tumors included five squamous cell carcinomas, four transitional cell carcinomas and one undifferentiated carcinoma. Seven of the tumors were at early stages, including three noninvasive (TIS) and four superficial (T1 and T2) ones. This investigation indicates that selective cytologic screening in the high-risk group in Egypt is feasible and effective for the early detection of bladder carcinoma associated with schistosomiasis.

Adult↗