Biomedical subjects
Publications and source records attributed to A S Krasnov.
In 6 patients with sarcomas of the bones of the crus at different periods following radiotherapy the authors have revealed pathologic reconstruction of the structure of the tibia. A roentgenologic picture of the changes in the course of the dynamic observation of the patients and their treatment is presented. It has been demonstrated that the conservative treatment effective.
The data on 53 cases of bone injuries caused by radiation treatment for cancer of the uterus were analysed. The clinico-roentgenological signs of osteoradionecrosis (33), pathological fracture and dislocation (13), osteomyelitis (5) and radiation-induced sarcoma of bone (2) were considered. Lesions were found to occur most frequently in the upper flaring portion of the ilium and bones of the hip joints. Regular X-ray examinations of the pelvic bones are necessary for early detection of radiation injuries as well as conservative treatment to prevent such grave complications as pathologic fracture and osteomyelitis.
The results of examination of 12 patients with vertebral radiation injuries were analyzed. The authors considered clinical and x-ray signs of radiation osteoporosis (5), radiation osteonecrosis (7 patients), and complications in the form of pathological fractures of vertebral bodies. Vertebral radiation injuries were most frequently detected 6-12 yrs. after the discontinuation of radiotherapy.
Secondary tumors developed in the zone of exposure fields in 6 patients treated with radiation for different malignancies. Tumors appeared, on the average, 12 years after radiotherapy.
The authors have summed up their experience gained in the diagnosis and treatment of radiation injuries of the head and maxillofacial region developing after radiotherapy of malignant tumors (105 patients) and non-tumorous diseases (47 patients).
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Explore the source record for details and available documents.
Explore the source record for details and available documents.