PubMed Health⌕ Search

Biomedical subjects

A S Kuznetsov

Publications and source records attributed to A S Kuznetsov.

At least 37 records · Page 2Linked to original sources
PubMed1994

Genetic effects of testicular incorporation of 137Cs in mice.

A comparative estimation of the frequencies of genetic disorders induced in germ cells of male mice by a single or long-term exposure to incorporated 137Cs or to external gamma-radiation has been carried out. The frequencies of dominant lethal mutations induced by a single exposure were similar with both types of radiation. In stem cell spermatogonia the frequency of reciprocal translocations was significantly lower in the case of single 137Cs administration than upon external gamma-radiation. Upon long-term administration the genetic efficiencies of both types of radiation were similar.

Animals↗
PubMed1991

[The surgical treatment of the carotid sinus syndrome].

The experience with operative treatment of 27 patients with cardioinhibitory and mixed forms of the carotid sinus syndrome (CSS) is summarized. Continuous endocardial electrocardiostimulation contributing to effective rehabilitation of the patients is a method of choice in cardioinhibitory form of the CSS. Location of an endocardial electrode in the atrium for avoidance of the cardiostimulator syndrome development is preferable. Use of the method in mixed form of the CSS requires further investigation.

Adult↗
PubMed1991

[Carotid sinus syndrome: diagnosis, treatment and complications].

Continuous electrocardiostimulation was applied in 33 patients with the carotid sinus syndrome. Neither fatal outcomes nor complications occurred in the hospital period. Analysis of complications in the late-term period (follow-up from one to 22 months) allowed the conclusion that physiological stimulation of the heart (in the AAI regimen) is the optimal method for the treatment of the cardioinhibitory form of the syndrome. The management of the mixed form is still disputable.

Adult↗
PubMed1990

[Chromato-focussing of plasma low density proteins].

A few alternatives of the binding of healthy patients plasma low density lipoproteins (LDL) with anion exchanger PBE-94 were revealed. In the first case the main part of LDL did not bind to the gel and the isoelectric points of the minor subfractions were 5.8 and 5.3, and pI 4.1. In the second case about half of lipoproteins did not bind to the gel, and the isoelectric points of subfractions were 5.7 and 5.0; and pI 4.1. In the third case when all lipoproteins bound to the PBE-94, there were much more subfractions and their isoelectric points were 6.2, 5.8, 5.2, 4.9, 4.5 and pI 4.1. All LDL of the patients with ischemic heart disease bound to anion exchanger, and the part of subfraction with pI 4.1 was three or five times as great as the one of the healthy person. Increasing of the LDL subfraction with pI 4.1 was observed at prolonged keeping of the LDL obtained from the healthy person plasma. LDL isoelectric point distribution of the persons with carcinoma uterine cervix did not differ from the one of the healthy persons. Acetylation and hexanol modification resulted in the isoelectric point shift from 5.7 to 4.6 and to 4.3 in the case of LDL subfraction to be obtained preparatively using the chromatofocusing.

Acetylation↗
PubMed1990

[Complications of endocardial electric stimulation].

The results of the operative treatment of 277 patients with atrioventricular block and sick sinus syndrome were analysed. The primary implantation of the electrocardiostimulators (ECS) was performed in 211 (73.5%), the repeated one--in 76 (26.5%) patients. The complications of endocardial electrocardiostimulation developed in 58 (17.3%) patients, of them in 39 (14%), the repeated operative intervention was performed. Most frequently, the complications were conditioned by the quality of electrodes and ECG.

Aged↗
PubMed1989

[Use of transesophageal electrostimulation of the atrium and nitroglycerin test in the evaluation of the degree of risk of the development of cardiac complications after reconstructive surgery in patients with Leriche's syndrome].

By the method of transesophageal electrostimulation of the left auricle, 98 patients with Leriche's syndrome were examined. Of them in 51, the coronary disease was revealed. The degree of ischemic changes in the terminal part of the ventricular complex were defined by the rate of stimulation, depth of the ST segment shift, and duration of ischemic depression. The nitroglycerin test permitted to evaluate the anti-ischemic effect of the drug, quality and effectiveness of the preoperative preparation. In patients with negative or doubtful anti-ischemic effect, the risk of the development of cardiac complications increases.

Atrial Function↗
PubMed1989

[The distribution of glutamate receptors in cultures of the motor area of the rat cerebral cortex studied by an immunoelectron microscopic method].

The aim of the study was to analyse the distribution and localization of glutamate receptors in the cultured cells of the neonatal rat motor cortex, using immunoelectron microscopic technique, and monoclonal antibodies preliminary labeled with colloidal gold. Monoclonal antibodies against glutamate-binding proteins of the adult rat cerebral cortex were produced by means of hybridization of immune splenocytes with plasmocytoma cells. It was found that monoclonal antibodies labeled with colloidal gold could reveal selectively the localization of glutamate receptors on the membranes of neurons. Glutamate receptors were detected on differentiating neuron membranes only, being absent from the glia cell surface.

Animals↗