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Biomedical subjects

A S Mukhin

Publications and source records attributed to A S Mukhin.

At least 19 recordsLinked to original sources
PubMed1985

[Clinical characteristics, course and diagnosis of chronic progressive liver diseases in patients with a history of acute viral hepatitis].

Based on examination of 144 patients with chronic active hepatitis (CAH) and liver cirrhosis (LC) with a history of acute virus hepatitis (AVH) it was established that chronic progressive liver injuries of virus etiology with and without HB-antigenemia are characterized by the diversity of the clinico-laboratory findings determined by the involvement, in addition to the liver, of many organs and systems. The following variants of chronic AVH were recognized: (1) early development of chronic progressive liver injury due to AVH (40.4% of cases); (2) late occurrence of chronic progressive liver injury after a latent period of varying duration, namely up to 21-30 years and more (59% of cases). Late recognition of CAH and LC in patients with a history of AVH was caused, on the one hand, by a high rate of chronic progressive liver injuries after a long-term period, and on the other hand, by erroneous evaluation of extrahepatic lesions, which were the first symptoms of a chronic condition in many patients. Hepatitis virus B markers were detected in the blood serum of 44.5% of patients with CAH and LC with a history of AVH, mostly in men (55.3%) versus women (34.9%). In view of the difficulties of verifying liver injuries of virus etiology based on the laboratory research methods alone, one should be guided by a clinico-epidemiological approach to a study of CAH and LC etiology.

Adolescent↗
PubMed1982

[Intermediate filaments in the lung macrophages and endothelial cells in chronic alcoholism and suppurative-destructive lung diseases].

Accumulation of intermediate filaments in lung macrophages and endotheliocytes has been found in patients with chronic alcoholism and purulent destructive pulmonary diseases. Excess accumulation of cytoskeletal elements reflects cell dystrophy. The authors believe that impairment of macrophage function may favour the lingering of the suppurative process.

Alcoholism↗