[A method of determining the dose distribution in a homologous phantom in gamma-teletherapy by using wedge-shaped filters].
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Biomedical subjects
Publications and source records attributed to A S Pavlov.
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The experiments carried out on 129 athletes (gymnasts, weight-lifters and boxers) and 153 non-athletes have shown that sports training increases substantially the general and specific physical performance and elevates 2-2.5-fold the human resistance to thermal effects. The relationship between the signs of physical fitness of sportsmen and the values of their thermal resistance has been established. The procedure and scale of evaluating the thermal resistance of man have been developed.
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The analysis is presented of combined treatment of locally advanced prostatic cancer (LAPC), stage T3NXM0, in 158 LAPC patients treated in 1998-2002. The patients were divided into four groups: group 1 (n=72) received hormones in parallel with radiation, group 2 (n=52) received only hormones, group 3 (n=27) received radiotherapy after failure of long-term (1 year and more) hormone therapy, group 4 (n=7) was given teleradiotherapy only. 3-year recurrence-free survival in patients with LAPC showed advantage of the combined treatment (82 +/- 0.1%) vs hormone (56 +/- 0.1%) or radiation (69.3 +/- 0.1%) therapy alone. It provides a high local control over the primary tumor and an increase of survival, prolongs distant metastases free period, improves the patients' quality of life and their adaptation.
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Parameters of work capacity (general, physical, mental, special) of exercising cadet-pilots were measured. It was found that during exercise-induced hyperthermia their work capacity initially increased and then decreased. When rectal temperature reached 38.74 +/- 0.01 degrees, the best results, i.e. those that were 28.1% better than the baseline, were seen in physical tests (work on the apparatus) and in seven mental tests. This level of hyperthermia attained by muscle work in a thermoneutral environment brought about adequate mobilization of cardiac rhythm regulation and spyrographic parameters whose price was not superior to physiological limits. It appears that the development of exercise hyperthermia is not due to the drive of the thermoregulation system to return to thermal homeostasis, as it is suggested by the current concepts of homeostasis, but, conversely, its drive to reach a higher level of thermoregulation (1.5 degrees higher) which is characterized by the best results of work as well as by adequate mobilization of the leading functional systems of the human body.
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