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Biomedical subjects

A S Rocha

Publications and source records attributed to A S Rocha.

43 records · Page 3Linked to original sources
PubMedDate not supplied

[Hyponatremia: study of its epidemiology and mortality].

To determine the prognosis of hyponatremia in an unselected population, we collected clinical and laboratory data and determined the outcome of hospitalization for all hyponatremic patients in a general hospital during a three month period. Fourty-nine episodes of hyponatremia were analyzed. More than 90% of them were observed in hospitalized patients and were of dilutional type, and 34% were classified as severe hyponatremias (Nas less than 118 meq/l.). Diuretics plus salt restriction without water restriction were the main identifiable causes. Neurological disturbances were observed in 10.8% of patients and persisted in 4.3% of then after the treatment. Slow correction of hyponatremia was the treatment used in these patients (0.16 +/- 0.004 meq/l.h). Ten patients died, but in only one case the dead could have been caused by hyponatremia. The results showed that the morbidity and mortality of the hyponatremia is low in our institution, few patients had neurological disturbances and a favorable outcome in all of them was obtained with a slow correction of hyponatremia.

Adolescent↗
PubMedDate not supplied

[Catatonic syndrome caused by autoimmune disease: spontaneous remission].

The psychiatric manifestations of systemic lupus erythematosus and other autoimmune diseases, which may precede by many years systemic involvement, should be held in mind by both the internist and psychiatrist. This case report focuses on a female catatonic patient without metabolic disturbances, whose evolution did not suggest a schizophrenic disorder. Immune complexes were demonstrated to be present in cerebrospinal fluid (CSF) obtained during psychotic crisis and immunologic tests showed circulating immune complexes with a positive antinuclear factor. (1/800) and a nucleolar pattern with immunofluorescence. The psychiatric picture receded concomitantly with a fall in CSF immune complexes and with an increase in circulating immune complexes, without the administration of immunosuppressive drugs. The catatonic syndrome is a rare manifestation in patients with autoimmune disease and few cases have been reported without systemic manifestation. This report emphasizes the need for increased awareness of the psychiatric effects brought about by autoimmune diseases and shows that CSF immune complexes are valuable markers for their diagnosis.

Adult↗
PubMedDate not supplied

[Prognostic accuracy and efficacy of treatment at intensive care units evaluated by the APACHE II system].

The APACHE II system can stratify acutely ill patients on hand of simple physiological measurements. In a retrospective study, 121 patients were stratifyed in regard to the mortality rates in three groups: first one with the mortality rate of 10% second one with 47%, and the third one with 100%. Mortality rates predicted and observed were similar (40.5% and 39.7%, respectively, p greater than 0.8; 95% confidence interval 31.8% to 49.7%). The APACHE II system is useful for accurate stratification of patients and the evaluation of treatment efficacy.

Brazil↗
PubMedDate not supplied

[Renal insufficiency due to lymphomatous infiltration of the kidney: report of 3 cases and review of the literature].

Renal failure in patients with lymphoma or leukemia may be brought about by different causes, including ureteral obstruction, hypercalcemia, hyperuricemia, amyloidosis, immunologically mediated nephrosis and paraproteinemic nephropathy. Lymphomatous or leukemic infiltration of the kidneys is a frequent finding at autopsy but is rarely seen as a cause of renal failure. In this report three patients with lymphomatous infiltration of the kidneys causing renal failure are described. Clinical and laboratory criteria for establishment of diagnosis in such cases are suggested. Using these diagnostic criteria, a renal biopsy may not be necessary.

Acute Kidney Injury↗