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Biomedical subjects

A S Sanac

Publications and source records attributed to A S Sanac.

6 recordsLinked to original sources

Evaluation of congenital Brown's syndrome with magnetic resonance imaging.

The magnetic resonance (MR) findings in congenital Brown's syndrome were investigated. Sixteen involved eyes of 12 patients were compared with 20 eyes of 10 controls. An enlargement of the tendon-trochlea complex was observed in congenital Brown's syndrome. In addition, the appearance of the tendon-trochlea complex was irregular in shape and of intermediate signal intensity. The MR appearances in patients with a satisfactory or poor response to surgery did not show any significant differences from each other or from those in patients who had not undergone surgery. This was also the case for the patient with spontaneous improvement. The MR examination in congenital Brown's syndrome suggested that the abnormality was located at the tendon-trochlea complex but clinically it does not give a clue about the outcome of the disease.

Adolescent↗

Factors influencing the successful outcome and response in strabismus surgery.

In this retrospective study based on 140 esotropic and 51 exotropic patients, the factors influencing successful outcome and response to strabismus surgery were investigated. Thirteen independent variables were chosen. The pre-operative deviation was found to be the only discriminant factor for early and late successful surgical outcomes in esotropic patients. For exotropic patients the visual acuity of the left eye was the discriminant factor for early successful surgical outcome. In esotropic patients the response to surgery increased with increasing amounts of pre-operative deviation. It was lower for patients with older age of onset and larger amounts of medial rectus recession. For exotropic patients the response to surgery was higher for larger pre-operative deviations. Eliminating possible sources of error when determining the pre-operative deviation will improve the predictability of the response to surgery and surgical outcome.

Age Factors↗

Factors influencing success and dose-effect relation of botulinum A treatment.

Botulinum toxin type A (BTA) treatment is an alternative to strabismus surgery. In this retrospective study the data on 45 esotropic and 49 exotropic patients with concomitant strabismus who were treated with BTA were analysed for dose-effect relationship, the effect of repeat doses and amblyopia on success of botulinum treatment. The esotropic patients were treated with a total of 80 and exotropic patients with 91 injections. The deviations were corrected within 5 degrees of straight in 33% of esotropic and 18% of exotropic patients. In esotropic patients the effect was dose dependent. This relation was not shown in exotropic patients. The repeat doses of BTA corrected the deviation to the same extent as the primary ones for both esotropic and exotropic patients.

Adolescent↗

High myopia causing bilateral abduction deficiency.

We present two cases of degenerative myopia with abduction deficiency. Three mechanisms can explain the defect in the abduction: (a) the size of the long globe filling the space of the orbits, (b) the tightness of the medial recti due to long axis of the globe, and (c) longstanding esotropia becoming decompensated later in life. We believe that high myopia is not a well-known cause of abduction deficiency, and it should be considered in the differential diagnosis.

Adult↗

Unilateral enophthalmos in systemic scleroderma.

Atrophy of orbital fat is a reported complication of localized scleroderma but not of systemic scleroderma. Here we present a case of systemic scleroderma with unilateral enophthalmos. Orbital fat atrophy was the presumed cause on computerized tomography.

Adipose Tissue↗

A comparison of various methods of treatment of amblyopia. A block study.

The results of conventional occlusion, minimal occlusion and CAM treatment in the management of amblyopia have been investigated in two disparate populations from Cambridge, England and Ankara, Turkey. Each of these methods of treatment was equally effective as an initial therapy. However, if one form of therapy was ineffective or only partially successful, then further improvement can be obtained by using an alternative method. A quarter of the patients showed no improvement in vision at all despite vigorous and active treatment. It is suggested that minimal occlusion should be the first method of treatment but if this fails either or both conventional occlusion and CAM treatment should be used and therapy should not be abandoned until all these methods have been attempted.

Age Factors↗