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Biomedical subjects

A S Shishov

Publications and source records attributed to A S Shishov.

At least 19 recordsLinked to original sources
PubMed2003

[Documented case of recurrent herpes zoster].

The paper presents a comparative description of the clinical picture of herpes zoster observed in a patient twice in 1989 and 1997. For its differential diagnosis with herpes simplex, emphasis is laid on a difference between the concepts "relapse" and "recurrence".

Adult↗
PubMed1998

[Neuralgia and zovirax treatment of patients with herpes zoster].

AIM: To estimate the occurrence of postherpetic neuralgia (PHN) arising after acute period of herpes zoster (HZ) and determination of zovirax efficiency in PHN prevention. MATERIALS AND METHODS: Of a total of 102 patients with HZ aged 17-89 years, 20 patients aged 26-83 years were given zovirax. RESULTS: Acute pain syndrome in PHN was observed in more that one-third of HZ patients. Patients over 60 years of age were more predisposed to PHN. Zovirax reduced the duration of acute rash and its healing, decreased the number of patients with zoster-associated pain and PHN patients. CONCLUSION: Zovirax is effective and safe in preventing PHN in HZ patients.

Acyclovir↗
PubMed1996

[The Guillain-Barré syndrome in herpes zoster patients].

A rare case of Guillain-Barré syndrome associated with herpes zoster developed on the 7th day of eruption in the right dermatoma DII-III in a man of 51 years old. The peculiarities of the symptoms, current status, liquor changes have been analysed basing on the data from foreign literature on 24 cases of Guillain-Barré syndrome (polyradiculoneuritis) associated with herpes zoster.

Diagnosis, Differential↗
PubMed1992

[Virolex in the treatment of herpetic diseases of the nervous system].

The authors relate the results of the use of virolex (acyclovir), a new etiotropic agent, for the treatment of some herpetic lesions of the nervous system. The use of the drug for the treatment of herpetic encephalitis, one of the gravest forms of encephalitides, exerts a beneficial effect. In the course of the treatment, it is of paramount importance to adhere to the established time of therapy, since the disease may recur. The treatment with virolex of different forms of herpes zoster in children and adults brings about positive results as well.

Acyclovir↗
PubMed1991

[Acyclovir in the treatment of severe generalized forms of herpes zoster].

Aciclovir administration in 8 herpes zoster patients aged 14-74 to manage resistant generalized herpetic eruption, serous meningitis, meningoencephalitis resulted in a pronounced response in 5 of them. Aciclovir has the advantage of its effectiveness in spite of late treatment (on herpes zoster day 6-22). This is particularly important for those forms of the disease which manifest severe symptoms during the second phase, i.e. disseminated eruption, involvement of brain matter, etc. Two lethal outcomes due to pulmonary artery embolism were unrelated to the drug administration.

Acyclovir↗
PubMed1989

[Pathogenesis of herpes zoster].

Long-term follow-up of 2000 patients with herpes zoster (HZ) in the department of viral neuroinfections as well as special HZ studies provided evidence for comprehensive evaluation of HZ pathogenesis. In addition to peripheral nervous system involvement, HZ is shown to cause systemic disorders typical for neuroviral infections. The principles of adequate pathogenetic therapy are validated. It is believed that relevant pathogenetic studies contribute to the development of general pathology.

Adult↗
PubMed1988

[Encephalitis in the acute period of herpes zoster in children].

The data from the author's files and literature are reviewed with respect to the occurrence, clinical characteristics and treatment of encephalitis in children with herpes zoster. A differential-diagnostic table is designed to present the clinical features of this form of encephalitis in different age groups and infantile encephalitis in chickenpox and herpes simplex.

Acute Disease↗
PubMed1987

[Epidemiology of herpes zoster. The herpes zoster patient as a source of infection with chickenpox].

The authors analyse the inpatient findings accumulated from 2,179 observations on herpes zoster cases for 10 years. The clinico-epidemiological characterization of herpes zoster patients as the potential source of chickenpox infection is presented. The clinical data speak for the droplet transfer of the agent (varicella zoster virus) in this infection, which has permitted the formulation of exact practical recommendations of quarantine and isolation measures in the focus of herpes zoster.

Acute Disease↗
PubMed1985

[Immunologic characteristics of the pathogenesis of herpes zoster].

Patients suffering from herpes zoster were subjected to immunological studies including the determination of the levels of the main immunoglobulin classes (IgA, IgM, IgG) in 102 subjects and the blast transformation test (19 subjects). Sufficiently tense humoral immunity and low reserve potentialities of cell-mediated immunity were discovered. Based on the data obtained the authors point to the necessity of using immunocorrecting agents, particularly levamisole, in combined therapy of herpes zoster.

Adult↗
PubMed1983

[Levamisole in the treatment of different forms of herpes zoster].

Fifty patients with early stages of herpes zoster (23 patients with the ophthalmic form and 27 with other localizations of the lesion) were treated with levamisol, since it was assumed that the disease is caused by the activation of the varicellazoster virus in association with cellular immunodeficiency. The control group consisted of 63 subjects, including 26 with the ophthalmic form. Beneficial results such as faster skin clearance and fewer days of hospitalization suggest that this agent should be recommended for combined treatment of patients suffering from herpes zoster.

Adult↗