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Biomedical subjects

A S Starikov

Publications and source records attributed to A S Starikov.

At least 19 recordsLinked to original sources
PubMed2004

[Neurophysiologic and neuropathological analysis of Parkinson's disease and its treatment with stereotaxic method].

Complete stopping of tremor or its essential reduction have been achieved in 55 of 66 patients with Parkinson's disease. In 3 cases, there was a fatal outcome. The microstructural changes of nigrostriatal, thalamus and neocortex neurons are presented, and biopotentials led from these structures, along with clinical and neurophysiological effects of electrostimulation of thalamic and subthalamic regions, are evaluated. The results obtained in the study are used for explanation of tremor mechanism.

Adult↗
PubMed1997

[Neurologic manifestations of sarcoidosis].

126 patients with histologically verified mediastinal-pulmonary legions were examined in terms of neurologic manifestations of sarcoidosis. Systemic psychoneurologic observation of all patients was performed by continuous method. Neurologic disorders were nonmalignant, chronic, latent or transitory. Stable, acute or severe manifestations were registered quite seldom. Sensory, autonomic, neuroendocrine and neuropsychologic disorders prevailed in clinical picture.

Adult↗
PubMed1996

[The function of the segmental motoneurons in Wilson-Konovalov's hepatocerebral dystrophy].

12 patients were examined by means of stimulative electromyography. Chronaximetric studies were carried out in 18 patients. The maximal amplitude of H-potential revealed the decrease of reflex excitability of the motoneurons pool. The stimulus value which is necessary for evoking H-reflex of liminal size testified the high reflex excitability of some alpha-motoneurons part. These motoneurons may take part in hyperkinesis development. The direct electrical excitability of motor units was elevated that was confirmed by motor response values. The motor analyzer functional rearrangement was revealed after stereotaxic operations as evidenced by dynamics of H-reflex and M-response parameters.

Adolescent↗
PubMed1993

[The electrical excitability of the peripheral motor neuron in parkinsonism].

Chronaximetry and stimulation electromyography were used in examination of 22 and 18 parkinsonian patients, respectively. The maximal amplitude of H-potential, the ration of the amplitude of the reflex to motor response and other parameters evidenced reduced reflex excitability of the motor neurone pool. The intensity of the stimulus sufficient to evoke threshold H-reflex indicated enhanced reflex excitability of the motoneurons which are likely to form passive tremor. As shown by motor response parameters, direct electric excitability of the motor units was high. Following stereotactic treatment, H-reflex and M-response shifted in the direction of increasing motor units excitability. These changes characterize functional rearrangement of the motor analyzer and correspond to a clinical response.

Adolescent↗
PubMed1992

[Nonspecific resistance and the immunological indices in brain contusion].

As many as 55 healthy persons and 69 victims with brain contusion of medium and severe degree were examined. Inhibition of cellular immunologic reactions and attenuation of nonspecific resistance as well as increase of immunoglobulins, immune complexes and cerebral antibodies were revealed. These changes were found to be more pronounced in a severe brain contusion.

Adolescent↗
PubMed1981

[Electromyographic indices in parkinsonism].

Using the methods of general and stimulation electromyography 53 patients suffering from parkinsonism were examined. The electromyographic findings were compared with the clinical ones. An idea concerning the role of alpha- and gamma-mononeurons and Renshaw's inhibitory interneurons in the origin of the parkinsonism syndrome is suggested.

Adult↗
PubMedDate not supplied

Functional state of segmental motoneurons in Wilson-Konovalov hepatocerebral dystrophy.

Stimulatory electromyography was used to investigate 12 patients, and chronaximetric investigations were performed in 18. Peak H-potential amplitudes indicated reductions in reflex excitability in the motoneuron pool. The stimulus size required for inducing threshold H-reflexes demonstrated a high level of reflex excitability among those alpha-motoneurons probably involved in generating hyperkinesia. Motor response parameters showed the direct electrical excitability of motor units to be elevated. Changes in H-reflex and M-response parameters demonstrated functional rearrangement of the movement analyzer after stereotaxic surgery. The functional states of the alpha- and gamma-systems are discussed.

Adolescent↗
PubMedDate not supplied

Electrical stimulation of the brain in Wilson-Konovalov hepatocerebral dystrophy (a neuromorphological and neurophysiological analysis).

Stereotaxic surgery was performed in 27 patients. Complete elimination of or significant reductions in hyperkinesia were obtained in 17 cases; five patients died. There was no correlation between the severity of clinical manifestations of hepatocellular dystrophy and the relatively normal quantitative measures of cortical and subcortical biopotentials, which were produced on a background of microstructural changes affecting neurons in these regions. It is suggested that qualitative significance of these biopotentials is that they carry an excess pathological spike activity resulting in hyperkinesia. This is supported by the fact that hyperkinesia was suppressed after surgical destruction of the ventrolateral nucleus of the thalamus and subthalamic structures.

Adolescent↗
PubMedDate not supplied

[The application of variational cardiointervalography for optimization of anesthesia in outpatient surgery].

The vegetative regulation condition was investigated by the method of variation cardio-interval-graphy in patients who underwent the intravenous anesthesia in the outpatient setting. The experience of using, on the differential basis, the sympathomimetic and vagotonic anesthetics for different-type vegetative tonus was analyzed. An optimal state in the vegetative regulation of the cardiovascular system, a stable hemodynamics and an adequate post-narcosis rehabilitation in the anesthetic management of one-day surgery were ensured owing to the suggested method in choosing an anesthetic.

Adrenocorticotropic Hormone↗
PubMedDate not supplied

[The electromyographic analysis of trembling hyperkinesis in Wilson-Konovalov's hepatocerebral dystrophy].

Global electromyography was applied in the examination of 20 patients with Wilson-Konovalov's hepatocerebral dystrophy before and after stereotaxic operations. The origin of volley muscular activity is explained on the basis of segmental reflexes known in neurophysiology: indirect relief of alpha-motoneurons from the primary terminals of the spindle, autogenous, recurrent and reciprocal inhibition of alpha-motoneurons.

Adolescent↗
PubMedDate not supplied

[Bioelectical activity of the brain in parkinsonism before and after stereotaxic operations].

The bioelectrical activity of the brain was studied in 85 patients. The bioelectrical potentials were recorded directly from the cortex of the cerebral himispheres and the subcortical structures of the brain. Clinical and electroencephalographic comparisons were made. Functional reorganization of bioelectrical potentials after stereotaxic operations is shown.

Adult↗