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Biomedical subjects

A S Synovets

Publications and source records attributed to A S Synovets.

At least 19 recordsLinked to original sources

[Effect of kallikrein and its inhibitor on absorption from the abdominal cavity in peritonitis].

Experiments were carried out in 195 albino rats. It was established that in acute peritonitis the rate of absorption of the colloid dye (tryptan blue) was sharply decreased. Kallikrein somewhat increased the absorption rate, especially at early terms while the inhibitor (kontrikal) was shown to substantially decrease it. The mode of injection (intravenous or intraperitoneal) failed to influence manifestations of the biological effect of the drug. The data obtained show that a disturbed absorption from the abdominal cavity may be corrected in acute peritonitis by injections of kallikrein.

Abdomen↗

[Effect of elastase inhibitor on proteolytic enzyme activity in experimental wounds].

The protease activity of the wound walls and in the wound washings during the experimental skin and muscular wounds treatment with a Trieline-containing ointment, which is an inhibitor of the elastinase, and with some other proteolytic enzymes has been determined on white rats. It is suggested, that the application of such inhibitors suppresses the catabolism rocesses and stimulates the regenerative ones.

Animals↗