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Biomedical subjects

A S Truswell

Publications and source records attributed to A S Truswell.

At least 19 recordsLinked to original sources

A national food policy for prevention of CHD?

There is an increasing recognition of the importance of diet in the prevention of CHD. Dietary recommendations of various authoritative bodies are summarized. There is now a concensus of opinion concerning certain nutritional changes needed. These have important implications for education, agriculture, food labelling and food subsidies. It is concluded that a national food policy is needed, but that this should come from education and persuasion and not from compulsion.

Coronary Disease

Diet and nutrition of hunter-gatherers.

The diets and nutrition of hunter-gatherers are discussed with the !Kung Bushmen (San) of the Dobe area, Botswana as the example. In general they show no qualitative deficiency of specific nutrients though they are thin and may be undernourished (by our standards) at some seasons. They show little or no obesity, dental caries, high blood pressure or coronary heart disease; their blood lipid concentrations are very low; and they can live to a good old age if they survive infections or accidents.

Adolescent

Short-term effect of coffee on blood fibrinolytic activity in healthy adults.

Ingestion of coffee was followed after one-half and one hour by shortening of whole blood fibrinolysis time. The amount of coffee was equivalent to a heaped teaspoonsful and a standard brand of instant coffee was tested. The effect was laregly lost when decaffeinated coffee was taken. It appears that the caffeine in the amounts of coffee ordinarily consumed stimulates fibrinolytic activity but 2 of the 12 subjects were resistant to the effect.

Adult

The effect of wheat fibre on plasma lipids and faecal steroid excretion in man.

1. The effect of isoenergetic substitution of bran and wholemeal bread for white flour and white bread was investigated in six healthy volunteers in a metabolic unit. 2. A 21 d high-fibre experimental period was preceded and followed by a 14 d control period, so that each experiment lasted 7 weeks. Blood samples were taken on each of the last 3 d and faeces collected (using carmine markers) for the last 6 d of each diet period. 3. Plasma cholesterol, triglycerides and serum calcium concentrations were not altered by the addition of wheat fibre. 4. Wheat fibre caused a significant increase in faecal bulk and frequency. Faecal steroid excretion was the same in the last week of the first control and the high-fibre periods but increased in the subsequent control period.

Adult

Effect of citrus pectin on blood lipids and fecal steroid excretion in man.

Citrus pectin (15 g/day) was added for 3 weeks to metabolically controlled diets in nine subjects. Pectin was consumed with fruit and sugar as a gel in divided doses with meals. Plasma cholesterol concentrations were reduced by a mean of 13% (P less than 0.001). Fecal fat excretion increased by 44% (P less than 0.001); neutral steroids by 17% (P less than 0.001) and fecal bile acids by 33% (P less than 0.02). Plasma triglyceride levels did not change.

Adult