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Biomedical subjects

A Said

Publications and source records attributed to A Said.

50 records · Page 3Linked to original sources
PubMed1975

Biochemical and haematological aspects of anaemia associating protein energy malnutrition (PEM).

Haematological as well as biochemical parameters assessing anaemia associating protein energy malnutrition PEM were estimated. Data revealed that controls studied have a relatively lower Hb, Ht, and R.B.C.S. count than European standards. Hypochromic anaemia was predominant in 83.3% of moderate Kwashiorkor being normocytic in 50% and microcytic in 33.3%. In severe KWO anaemia was normocytic in 42% and microcytic in 19.2%. Normochromia was found in 9.7% and hypochromia in 29%. Macrocytosis was found in 38.8% in severe KWO. In marasmus, normocytic anaemia was revealed in 74% of the 2nd. grade being normochromic in 82% and hypochromic in 40%. Macrocytic anaemia was detected in 26%. In 3rd. grade subjects normocytic normochromic anaemia occurred in 70% of the cases. Macrocytosis was encountered among 30% of the cases. Serum iron and transferrin level dropped in both KWO and marasmus, the extent of decrease was greater in the former. The percent transferrin saturation was elevated in severe cases. Particularly severe KWO and marasmic KWO.

Anemia, Hypochromic↗
PubMedDate not supplied

Effect of protein energy malnutrition (PEM) on spermatogenesis in rat testis.

In this work 60 male albino rats were subjected to a feeding experiment aimed to study the influence of protein free and reduced diets on normal function of rat testes. It was shown that the PEM exerts adverse effects on testicular function, the nature and severity of these effects depend on the duration of the deficiency state. Histological examination of rat testis, revealed that the spermatogenesis is arrested at spermatogonium stage in rats fed on protein free diet, and at primary and secondary spermatocyte stage in rats fed on normal but reduced diet.

Animals↗
PubMedDate not supplied

Intestinal and renal tubular amino acid absorption in oedematous forms of protein-calorie malnutrition.

The level of total amino acids was determined in plasma and urine in cases suffering from ocdematous forms of PCM before and after receiving a single dose of each of cysteine, tryptophan and lysine. The increase in plasma amino acids following dosing was less in malnourished cases than in controls. Fasting urinary amino acid content in malnourished subjects was higher than in controls and so was also the ratio of urine amino acids collected after dosing to the fasting level. As the study revealed that protein depletion inhibits intestinal absorption and tubular reabsorption, parenteral administration of amino acids is recommended during treatment to escape intestinal loss. Excess oral protein should be given in food to compensate for losses via the gastro-intestinal and renal tracts.

Amino Acids↗
PubMedDate not supplied

Protein-calorie malnutrition (PCM) in Egypt VII--Urinary enzymes as an index of renal involvement.

Enzymuria observed in PCM, especially in severe cases, does not seem to be a simple reflection of the increased serum values and suggests renal involvements. A number of factors among which are :- lowered clearance threshold for certain enzymes as well as rapid wear and tear or renal cells seem to participate in the causation of such enzymuria. Urine enzyme analysis may reflect the extent and state of renal pathology among different forms of PCM.

Acid Phosphatase↗