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Biomedical subjects

A Salud

Publications and source records attributed to A Salud.

9 recordsLinked to original sources
PubMed1992

Endobronchial metastases in colorectal adenocarcinoma.

Between 1982 and 1990, 2388 bronchoscopic examinations were carried out in patients with cancer in our hospital. A diagnosis of endobronchial metastasis was established in 30 patients (2.09%), with the following primary tumors in descending order of frequency: breast, large bowel, melanoma, neuroblastoma, leiomyosarcoma and endometrial. Despite the rarity of endobronchial metastases secondary to colon adenocarcinoma, we were able to study 3 cases from our Center. In one case the diagnosis of endobronchial metastasis was simultaneous with that of the primary tumor, and in the other 2 this metastatic complication occurred 16 and 42 months, after the original diagnosis. When this complication occurred, the stage of the disease was advanced in all 3 cases: 2 were Dukes' stage C and one stage D. Although this metastatic location usually implies a very negative prognosis as regards life expectancy, it did not seem to significantly reduce the latter in our patients.

Adenocarcinoma↗
PubMed1992

Cavitary pulmonary metastases in transitional cell carcinoma of the urinary bladder.

About 4% of metastases to the lung eventually evolve into cavitary lesions. The origin of these lesions are squamous cell carcinomas in 69% of cases and adenocarcinomas in the rest. Lung metastases develop in 20% of patients with transitional cell carcinomas of the urinary bladder (TCB), usually as multiple nodules. The cavitation of these metastases is an unusual finding, and a review of the literature has revealed only 7 cases of cavitary metastatic lesions from TCB. We add 2 further cases with cavitary metastases and study their clinical and radiographic features, in comparison with those previously described in the literature.

Aged↗
PubMed1991

[Ovarian cancer in a female patient with von Recklinghausen's disease].

A 29-year-old female with von Recklinghausen's disease developed ovarian epithelial cancer. Neurofibromatosis is a dominant autosomal disease predisposing to a wide range of tumors. The association between neurofibromatosis and malignancy was reviewed, analyzing the relevant features for the present case.

Adult↗
PubMed1991

Orbital metastases from transitional-cell cancer of the urinary bladder.

Transitional-cell cancer accounts for 90% of the histological types of cancer of the urinary bladder. This tumor most often spreads towards the lymph nodes, lung and bones, but other much more infrequent metastatic sites such as the orbit, have also been described. We report on 2 patients with transitional-cell bladder tumors that developed metastases to the orbit.

Carcinoma, Transitional Cell↗
PubMed1990

[Treatment with interferon of systemic Langerhans-cell histiocytosis in an adult].

We report an adult patient with systemic Langerhans' cell histiocytosis (LHX), who was refractory to multiple chemotherapy courses and in whom a partial clinical and biological 3-month remission was achieved with alpha-2-interferon. The patient's response was associated with an increase in the rate of natural killer cells and to a return to normal of the H/S T-lymphocyte ratio. Immunological abnormalities have been reported in this condition, and it is now accepted that the most important one is a decrease in suppressor lymphocytes. However, it is not known whether these abnormalities are endogenous or exogenous. The experience with modifiers of the biological response for the treatment of LHX is scanty, but the probable immunological pathogenesis of the condition justifies a therapeutic trial of those agents in patients not responding to conventional therapy.

Adult↗