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Biomedical subjects

A San José

Publications and source records attributed to A San José.

At least 19 recordsLinked to original sources

[Psychoactive drug use in nursing homes].

BACKGROUND: Our purpose was to know the use of psychoactive drugs including neuroleptics (NL), benzodiazepines (BNZ) and antidepressants (AD) in nursing homes (NH) in the city of Barcelona. METHOD: Cross-sectional descriptive study of 384 clinical records of people living in 19 NH. The correct use of drugs was estimated by Garrad's and Beers et al criteria. RESULTS: Average age (SD) of residents was 83 years (2.0). The average consumption of drugs was 5 (2.7); 248 individuals (64.6%) were taking at least one psychoactive drug: 81 (21%) consumed NL, 179 (46.6%) BNZ and 73 (19%) AD. 48 (12.5%) NH residents consumed long-acting BNZ and 26 (6.7%) had surpassed the recommended time of consumption for short-acting BNZ. In 21 (26%) NH residents who consumed NL, its use would not be justified. CONCLUSIONS: It is necessary to reduce the use of long-acting BNZ, to encourage a correct use of NL and to achieve a correct identification of depressive disorders in NH.

Aged↗

[Cardiac and hematological involvement in idiopathic hypereosinophilic syndrome. Study of 12 cases].

BACKGROUND: The idiopathic hypereosinophilic syndrome (IHS) is a rare entity of unknown etiology. Hematological and cardiac involvement is predominant. A series of 12 patients with this syndrome, initiated in 1982, is described. METHODS: Cardiological study by repeated echocardiograms and hematological study in peripheral blood and bone marrow upon initiation of the disease were performed. RESULTS: Median follow up was of 48 +/- 31 months. Males predominated (75%) with mean age being 55 +/- 15 years. The principal organs or systems involved were the heart (50%) and the nervous system (41%). Of the 6 cases with cardiac involvement only 2 had clinical manifestations. The remaining 4 patients were diagnosed from echocardiographic changes with the principal alterations observed being: atypical occupation of the ventricles, endocardial thickening and mitral and tricuspid subvalvular cumulus. Echocardiographic follow-up only showed changes in one case. Hematological involvement was characterized by moderate leukocytosis with hypereosinophilia formed by mature eosinophils, conservation of other hematopoietic series, absence of blasts in peripheral blood, finding suggestive of diseosinophilopoiesis and appearance of myelofibrosis and cytogenetic alterations. Survival at four years was 58%. CONCLUSIONS: In the series studied cardiac involvement is frequent, being principally diagnosed in a subclinical phase and with a very slow echocardiographic evolution. At a hematological level changes typical in myelodysplastic syndromes and myeloid leukemia were observed.

Adult↗

[Idiopathic inflammatory myopathy. Analysis of 31 patients].

A series of 31 patients suffering idiopathic inflammatory myopathy (IIM); we describe the extramuscular manifestations, specially pulmonary, the association to neoplasia, the histopathological characteristics, and their response to treatment. Fourty three percent of IIM patients presented a pulmonary involvement, 9% presented an associated neoplasia. The histopathological study allowed us to clearly differentiate dermatomyositis and polymyositis within IIM. 65% of patients initially responded to glucocorticoids and the most usefull therapeutic alternatives were azatioprine and cyclosporin-A.

Adult↗

[Aspects of pre-operational information of the patient in emergency surgery].

BASIS: Under the conditions in which hospital activity is carried out, information can present important shortcomings. The aim of our study is to analyse the perception held by the patients of the information provided before an emergency surgical operation. MATERIAL AND METHODS: The study was carried out by means of a survey to 115 patients (66 men and 49 women) before they received emergency surgery, in the Hospital de Navarra, in the months from March to December, 1999. The sample was selected when the researchers responsible for this work were on duty. The majority of the operations corresponded to general surgery (39.1%) and traumatology (42.6%). The average age was 45.7 years (SD = 21.57, range 15-85 years). RESULTS: The results express the relations and differences between the degree of information requested and the cultural level, age and sex of the patient. Eighty seven per cent of the patients had been informed about the operation they were about to undergo. Seventy eight per cent had not signed their consent for such an operation and the doctors signature appeared in only 6%. Some 8.7% did not feel they had received information from anybody. Seventy three per cent understood the information provided. The information was considered insufficient by 44.6% of the patients. Forty five per cent were able to express their doubts to the informant, and 96.4% of them were satisfied with the clarifications. CONCLUSIONS: The patients considered themselves to be informed about the surgical process, but very few of them about the most relevant sensations they were to experience in post-operation. Information should be supplied that includes both types of content.

English Abstract↗