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A Sanfilippo

Publications and source records attributed to A Sanfilippo.

48 records · Page 3Linked to original sources
PubMedDate not supplied

Canadian consensus recommendations for the measurement and reporting of diastolic dysfunction by echocardiography: from the Investigators of Consensus on Diastolic Dysfunction by Echocardiography.

Abnormalities of diastolic filling are increasingly recognized as a cause of symptoms and predictors of outcome in patients with most forms of heart disease. Noninvasive assessment of diastolic filling is possible in almost all patients, but accurate evaluation must relate echocardiographic Doppler measurements to the complex physiologic and hemodynamic factors responsible for normal and abnormal filling. This evaluation has been facilitated by recent correlation of Doppler measurement of mitral and pulmonary venous inflow with hemodynamic studies. These studies have confirmed that when a careful, integrated approach is taken, Doppler flow patterns can document a progressive pattern of abnormality in many conditions. Impaired left ventricular (LV) relaxation is seen early and is recognized by a decrease in early transmitral LV filling and an increased proportion of filling during atrial contraction. As abnormalities progress, increasing LV chamber stiffness and elevated left atrial pressure lead to a "pseudonormal" filling pattern that previously has caused considerable confusion. This can be unmasked by careful evaluation of pulmonary venous inflow and the use of the Valsalva maneuver. When marked diastolic abnormalities are present, LV filling has restrictive features characterized by rapid early filling, a very stiff left ventricle with high filling pressures, and a poor prognosis. Routine measurement of indexes of diastolic filling have been hampered by uncertainty as to what should be measured, what techniques should be used, definition of normal values, and a clear method of reporting findings. This report represents the efforts of a Canadian consensus group to define a national standard for the performance and reporting of echocardiographic Doppler studies of diastolic filling.

Aged↗
PubMedDate not supplied

Changes in the lumbosacral segment of the spine due to overweight in adults. Preliminary remarks.

The Authors studied postural changes in the lumbosacral segment of the spine due to severe obesity in 28 young adults of both sexes. In particular, the preliminary degree of pelvic rotation caused by overweight was evaluated by studying the lumbosacral angle (LSA) amplitude, changes in normal static equilibrium of the spine and lumbar hyperlordosis in relation to the lordotic angle (LA) amplitude. Body Build Index (BBI), the lumbosacral angle and the lordotic angle were compared to determine if any correlations existed among the three. Even though the patient number was limited, pathologic values for both the LSA and the LA were found in all 28 subjects. The Authors found no correlation between LSA and LA increase regarding BBI; on the contrary, a correlation was evident between LSA increase and LA. A decrease in the LSA and LA values took place after reduction in body weight, after therapeutic intervention. The Authors believe that a one year follow-up is necessary to evaluate any long term decrease in the values of the above mentioned angles.

Adult↗