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Biomedical subjects

A Savage

Publications and source records attributed to A Savage.

15 recordsLinked to original sources
PubMed1992

[Malaria in the Dunkerque hospital center from December 1979 to December 1990].

Seventy-one cases of malaria were diagnosed in the hospital of Dunkerque from 1979 to 1990. Forty-five patients have been infected in the Comores islands. Among the 24 other imported cases, 17 (71%) have been contaminated in Western or Central Africa. One case of congenital malaria and one of malaria acquired by blood transfusion are also reported. Plasmodium falciparum was detected in 84.5% of the patients. The four human species were found among the Comorians. Two cases with abnormal forms of Plasmodium vivax were observed.

Adolescent↗
PubMed1991

High performance anion exchange chromatography of reduced oligosaccharides from sialomucins.

High performance anion exchange chromatography on pellicular ion exchange resins under high pH conditions with detection of sugars using a pulsed amperometric detector has been developed as a method for the separation and analysis of reduced oligosaccharides liberated from mucins by alkaline borohydride treatment. Ovine, bovine and porcine submaxillary mucins were used as models to develop the method. Although neutral reduced di-to tetraoligosaccharides were poorly retained on the column, a variety of sialylated reduced oligosaccharides could be separated efficiently. Treatment of the samples with sialidase and rechromatography identified the sialylated compounds in the elution profile. A striking finding was the greatly delayed elution times given by N-glycolylneuraminic acid containing compounds in comparison with the corresponding N-acetylneuraminic acid containing analogues. The elution profiles for the product from the mucins closely corresponded to those expected for the major oligosaccharides from these mucins. The procedures described will be useful for analysing sialomucins on a microscale without resorting to radiolabelling procedures.

Alkalies↗
PubMed1991

[Atypical forms of Plasmodium vivax. Apropos of a case].

In one case of human malaria imported from Gabon, abnormal forms of Plasmodium vivax are described; severe multiple infections of the host erythrocytes are noticed (up to 6 amoeboid trophozoites in a single red blood cell). Attention is drawn to the numerous morphologically abnormal intra-erythrocytic stages of P. vivax: severe multiple infections of red cells, parasites "ressembling" P. ovale, mature schizonts of small size, with reduced number of merozoites... The geographical distribution of P. vivax in Central Africa is discussed, with reflections on the factors allowing the importation of few P. vivax cases from this area.

Adult↗
PubMed1979

Abortion.

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Abortion, Legal↗
PubMed1979

Histological appearances of the gastric mucosa 15--27 years after partial gastrectomy.

Sixty-three patients, who had had a partial gastrectomy 15--27 years previously, were examined by endoscopy and multiple mucosal biopsies. No patient had a completely normal gastric mucosa; they showed varying degrees of gastritis, intestinal metaplasia, and dysplasia: 21% had significant dysplasia, and these are regarded as an 'at-risk' group requiring frequent follow-up examinations. One patient had severe dysplasia (carcinoma-in-situ), but no case of infiltrating carcinoma was found.

Adult↗
PubMed1979

Symptomatic hypomagnesemia associated with gentamicin therapy.

A 57-year-old male developed hypomagnesemia, hypokalemia and hypocalcemia during the course of repeated gentamicin therapy. Renal wasting of magnesium and potassium was demonstrated. Associated endocrine abnormalities included decreased level of serum immunoreactive parathyroid hormone and increased levels of plasma renin and aldosterone. Our findings are compared to those previously reported by other investigators.

Adult↗
PubMed1977

Granular cell myoblastoma of the biliary tree.

A granular cell myoblastoma of the common bile duct is described which caused episodes of jaundice in a young woman. Histological examination demonstrated a close association of the tumour with nerve fibres, tending to support the theory of origin from Schwann cells. The lesion is benign and after excision carries an excellent prognosis.

Adolescent↗
PubMedDate not supplied

IV drugs: assessing pupils in Botswana.

This small study set out to establish the abilities of a group of pupil nurses in a rural hospital in Botswana to accurately calculate intravenous driprates and drug dosages, and how targeted teaching could improve their performance. Thirteen pupils were asked to complete a seven-item questionnaire comprising set questions on intravenous therapy, then take a second questionnaire after receiving targeted teaching. Comparison revealed that two specific problems, related to dripsets and dilutent displacement, remained after teaching, but that improvements in scores in the 'incorrect with little immediate risk' and 'correct' categories had been achieved. The author suggests that formal testing and targeted teaching are appropriate methods of helping pupil nurses evaluate and improve their skills and knowledge base.

Botswana↗