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Biomedical subjects

A Schaudig

Publications and source records attributed to A Schaudig.

At least 19 recordsLinked to original sources

[Concepts in surgical therapy of kidney cancer].

Three new aspects of the operative treatment of renal cell carcinoma can be made out: 1. for the removal of tumor thrombus extending to the right atrium, the surgical technique of choice involves whole-body hypothermia and extra-corporeal circulation. Only in this way can these tumors be removed completely under good vision. 2. Provided the patient's contralateral kidney is healthy, even small peripheral renal tumors should be submitted to radical nephrectomy. The rate of concomitant small tumors is reported to be as high as 20, while the recurrent rate associated with local incision is just on 7%, and the risk of carcinomas developing in the contralateral kidney is only 1.8-3.8%. 3. Radical nephrectomy for tumor should continue to include the ipsilateral adrenal gland. Although in our own patients the incidence of simultaneous adrenal metastasis was only 1.4%, if the adrenal gland is left in situ, part of the renal capsule also has to be left behind, and the upper pole of the kidney dissected free, with the associated risk of disseminating tumor cells.

Adrenal Gland Neoplasms↗

Bacterial overgrowth in ileal reservoirs (Koch pouch): extended functional studies.

An absorptive, hormonal, bacteriological and morphological study was performed in 9 proctocolectomized patients with continent ileal reservoirs established for 2-57 months. Vitamin B 12 malassimilation (as assessed by the Schilling test and serum vitamin B 12 concentration), bile salt deconjugation (modified 14C-glycocholate breath test), increased stool fat excretion and high intestinal sodium loss with secondary hyperreninism/hyperaldosteronism were encountered in a large percentage of patients; proximal small intestinal absorption (serum parameters, xylose test) appeared intact. In reservoir stool samples total and differential bacterial cell counts yielded values close to a normal rectum flora. Morphologically (endoscopy, quantitative histology) the reservoir mucosa showed moderate to severe inflammation; structural changes were essentially absent and inflammation in the adjoining ileum was minimal. These results indicate that reservoir bacteria frequently produce disturbances in small intestinal function and that these may be found without secondary structural transformation of the mucosa.

Adolescent↗

[Incomplete lead fracture as a cause of bradyarrhythmia in patients with artificial pacemakers (author's transl)].

The fracture of a permanent cardiac pacing lead may be complete or incomplete. In the first case, the function of the pacemaker system will completely cease. An incomplete fracture, however, is defined as a capillary interruption of the wire and will lead to a loose connexion between both parts of the electrode. This, in turn, may result in sudden changes of the electrical resistance of the lead and, therefore, in alterations of the electrode voltage during the second part of the biphasic current wave delivered by the pacemaker; this voltage change--in the 10-mV-range--will inhibit a blocking demand pacemaker with an intermittent, irregular increase of the pacemaker escape interval as the corresponding ECG finding. Usually, this "oversensing" phenomenon can be eliminated by turning the pacemaker function to the fixed rate mode with a test magnet applied. -- Although this malfunction is more often seen with bipolar pacemaker systems and with epicardial wires, it may also occur in a unipolar, transvenous system. -- Among 2100 patients, we have seen this malfunction in 6 cases in whom other, even more rare causes--such as a defect of the electronic circuit of the pulse generator, muscle potentials, etc.--could be ruled out. The x-ray findings revealed no evidence of a lead fracture in any case. The diagnosis was established on the ECG, the examination of the surgically removed electrode in 2 cases, and the finding, that only the implantation of a new lead abolished the malfunction, whereas the implantation of a new pacemaker alone ws ineffective.

Bradycardia↗

[Mammary carcinoma].

Comments are made on controversial questions on the early recognition of mammary carcinoma with reference to the most important publications in the world literature and to our own experience. The decision between mastectomy and irradiation presupposes a histologically, cytologically, clinically or mammographically confirmed diagnosis. The extent of an operation must take cosmetic principles into consideration. Follow-up irradiation is unnecessary if no metastases are found in the axillary lymph nodes or in only one or two lymph nodes in the lowest layer near the mammary gland. Addional hormonal or cytostatic therapy does not improve the longterm results with all certainty.

Adult↗

[Resection for pulmonary metastases: results and prognosis (author's transl)].

From 1955 to 1975 in 25 patients lung surgery has been carried out because of intrapulmonary metastases of extrapulmonary malignant growth. 6 patients survived longer than 5 years. There was no relationship between survival time and length of the time interval between initial surgery (primary) and second operation (i.e. diagnosis of pulmonary lesion). On the other hand a definite relationship resulted for survival time and the size of the growth. In bad-risk patients surgery for metastatic lung cancer is not indicated, but it is very successful in selected cases.

Female↗