PubMed HealthSearch

Biomedical subjects

A Scheinin

Publications and source records attributed to A Scheinin.

At least 19 recordsLinked to original sources

Multifactorial modeling for root caries prediction.

The study was part of a series of investigations aiming at the development of diagnostic caries tests for screening of risk subjects. The material consisted of 100 adult subjects (mean 62 yr, range 47-79 yr), 50 of these under chronic medication. The series of tests included two chairside registrations, i.e. incipient demineralization of exposed root surfaces without cavitation (RD 1) and quantitation of visible plaque (VPT%), three microbiological tests for mutans streptococci, lactobacilli, and candida/yeasts and three tests on stimulated saliva, i.e. secretion rate, buffering capacity and sucrase activity. A thorough clinical examination was conducted at the baseline and 1-yr registration phases, caries being registered at a tooth surface level according to WHO recommendations separately for coronal and root caries. Considerably more root caries than coronal caries developed during the observation period. For coronal caries increment, the predictive value of any of the tests was not significant. For root caries, however, the association between several tests and prospective caries increment was significant. Subsequent multifactorial modeling yielded the highest predictive value to the combination of Past Root Caries Experience (OR 25.0, Visible Plaque (OR 4.2), Candida (OR 8.0) and Lactobacilli (OR 5.8). A positive finding of Past Root Caries (RDFS) or the combination of the other three tests (Can, LB, VPT%) as criteria for selection in screening for root caries produced good accuracy (84.0) and a relative risk of 5.5.

Aged

[The assessment of the caries risk in young adults].

Several factors for caries prediction have been proved in a one-year follow-up study on 73 patients. The white-spot lesions have proved to be a good criteria for caries prediction in this population. These lesions could be combined with the microbiological tests Dentocult SM and Oricult N or with the determination of the buffer capacity (Dentobuff), which did not much improve the prediction.

Adult

Perspectives on xylitol-induced oral effects.

The review covered xylitol-induced effects on oral health. Xylitol was considered virtually nonacidogenic and to possess specific and unspecific advantageous effects on oral health. It was shown to mediate nonspecific remineralization, while its demineralization-inhibiting and S. mutans-reducing effects were regarded as specific. The clinical trials and field studies indicated that partial substitution of dietary sucrose by low doses of xylitol was associated with a pronounced caries reduction.

Cariostatic Agents

Sucrose consumption and salivary sucrase activity in a 2-year longitudinal study.

Sucrose consumption data of the sucrose group (n = 33) of a 2-yr longitudinal study was plotted against salivary sucrase activity values obtained during this 2-yr period. The correlation coefficients varied between 0.194 and 0.551. The subjects were divided into high (greater than or equal to 10 mumol x min-1 x (10(-3)) and low (less than 10) sucrase activity subgroups. There were significant differences in the sucrose consumption and in intake frequency between these two subgroups. These findings give further support for the possibility of using sucrase activity for the estimation of the level of individual sugar consumption.

Adult

Screening of caries in children through salivary lactobacilli and yeasts.

The caries predictive value of salivary counts of lactobacilli and yeasts was evaluated in 298 children (from 6 to 11 yr of age) concurrently to a 3-yr xylitol field study in Hungary. On a group level the salivary yeasts and the combined information of lactobacilli and yeasts predicted the 3-yr caries increment acceptably. On an individual basis salivary yeasts had more power than salivary lactobacilli. At best the sensitivity and specificity of yeasts were 74% and 75%, and the combined information of lactobacilli and yeasts, 69% and 83%, respectively. Although the results were not that good in all subgroups of the study, they indicate the value of salivary yeasts in caries prediction either as a sole test or together with salivary lactobacilli.

Child