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Biomedical subjects

A Schmaman

Publications and source records attributed to A Schmaman.

At least 19 recordsLinked to original sources
PubMed1987

Blood gas pH and pulmonary response to the inhalation of low osmolar contrast media iopamidol and ioxaglate.

Effects of inhalation of diluted low-osmolar ionic ioxaglate and nonionic iopamidol 200 water-soluble radiographic contrast media on neonatal pig lung were evaluated. Our purpose was to assess the suitability of these substances for the radiologic investigation of upper gastrointestinal problems in human neonates in whom aspiration may occur. We used two-week-old baby piglets weighing 2.5-3.5 kg as the experimental model because they are similar in weight and size to a human neonate. The effects of intratracheal instillation of isosmolar contrast media were evaluated using the parameters of (1) blood gas exchange, (2) clinical status, (3) radiology, and (4) histopathology. The piglets showed no clinical or radiologic abnormality; blood gas exchange, initially impaired, rapidly returned to normal. Long-term (four days) follow up showed mild, self limiting but persistent infiltrates in the lungs at histology. We conclude that these diluted contrast media are suitable for upper gastrointestinal examination in neonates.

Administration, Inhalation↗
PubMed1985

Elastosis in malignant tumours.

Elastosis is common in infiltrating ductal and lobular carcinomas of the breast, occurring in approximately 90% of cases. It is also well described in some benign lesions of the breast and tumours of the salivary gland. Reports of venous elastosis in association with large-bowel carcinomas are rare. We describe elastosis in single cases of prostatic, gastric, bronchiolar-alveolar and cervical carcinoma.

Adenocarcinoma↗
PubMed1985

Aneurysmal bone cysts of the patella secondary to chondroblastoma. Case reports.

Three cases of aneurysmal bone cysts secondary to chondroblastoma of the patella are described. This association is not particularly uncommon, but its occurrence in the patella is unusual. Treatment consists of curettage and bone grafting; however, if the patella is grossly enlarged or distorted, patellectomy is preferable.

Adolescent↗
PubMed1980

Corrosive gastritis as a result of ferrous sulphate ingestion.

The toxicity of ferrous sulphate is discussed, with particular reference to fibrosis and stricturing of the stomach. This does not occur in every case, but occasionally, in spite of adequate treatment, ferrous sulphate produces local damage similar to that caused by acid. Endoscopy and barium studies are mandatory to assess the damage, and repeated checks should be undertaken, since late changes may take place as much as 6 years after ingestion. Gastrectomy is often necessary when severe scarring and fibrosis have resulted in damage to the stomach. The need for long-term follow-up of these patients is an important aspect of treatment.

Child, Preschool↗
PubMed1980

Arteriohepatic dysplasia: association of liver disease with pulmonary arterial stenosis as well as facial and skeletal abnormalities.

The clinical features and course of five children with the recently described syndrome of arteriohepatic dysplasia are presented. All had bilateral pulmonary arterial stenosis, proven at cardiac catheterization, as well as associated liver disease of varying severity. In one of the fatal cases, a hitherto undescribed anomaly was found--stenosis of the right coronary artery ostium. A viral etiology, eg, the congenital rubella syndrome, was considered most likely, but detailed investigations proved to be negative.

Abnormalities, Multiple↗
PubMed1977

Abdominal aneurysm in South African Negroes due to intimomedial mucoid degeneration.

Nine South African Negroes with abdominal aortic aneurysms due to intimomedial mucoid degeneration are described. These occurred in a younger age group than atherosclerotic aneurysms and with a female predominance. The aneurysms are not syphilitic in origin and are unlike atherosclerotic aneurysms. This form of abdominal aneurysm constitutes a distinct entity which is relatively prevalent in South African Negroes and which has hitherto received little or no emphasis and attention.

Adult↗
PubMed1977

Congenital thyroid cyst of ultimobranchial gland origin.

The ultimobranchial gland (UBG) is an endocrine gland which contributes C cells to the thyroid gland in mammals. Dysembryonic tissues derived from the UBG have been described as cystic bodies. The following case illustrates the criteria which characterize dysembryogenesis of the UBG.

Animals↗
PubMed1976

Angio-immunoblastic lymphadenopathy. A report of 3 cases.

Angio-immunoblastic lymphadenopathy (AILD) was diagnosed in 3 Black patients, AILD is a non-malignant disorder which resembles a malignant lymphoma clinically and morphologically. It is thought to represent an abnormal response of B lymphocytes to antigenic stimuli which are often therapeutic agents. The disorder usually affects adults of the older age group and the clinical course can be rapidly fatal, particularly if vigorous chemotherapy is given. Of the 3 patients with AILD, 2 died from complicating infections within 6 months after the initial diagnosis. The third patient was completely cured after short courses of prednisone and vincristine. It appears that in some patients the disorder may be completely reversible but whether these patients are at a greater risk of eventually developing a lymphoma is uncertain at the present time, and remains to be ascertained by their long-term follow-up.

Adult↗
PubMed1975

Giant cell tumour of the sacrum. A case report.

A case is reported of a giant cell tumour of the sacrum, an infrequent but well-recorded site for this tumour. The relatively benign histology of this neoplasm was not consistent with its natural history in this patient, nor with its resistance to treatment. An additional feature of interest and concern was the intense vascularity of the lesion.

Adult↗
PubMed1975

Unusual malignant tumours of the maxilary sinuses.

Six rare tumours of the maxillary sinus occuring in South African Blacks are described. The incidence of sarcomas and tumours of glandular epithelium in the nasal sinus region is discussed and the literature is reviewed.

Adenocarcinoma↗