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Biomedical subjects

A Schuette

Publications and source records attributed to A Schuette.

4 recordsLinked to original sources
PubMed2002

MSG.

The Microgravity Science Glovebox (MSG) has been designed as a modular multi-user facility for performing a wide variety of materials, combustion, fluids and biotechnology investigations in the microgravity environment. Primarily it provides an enclosed and sealed Work Volume (WV) equipped with lighting, mechanical, electrical, data, gas and vacuum connections, and thermal control. The WV is provided with built-in glove ports for safe handling by the crew and isolates the item under investigation from the operator area and the general ISS environment. An attached Airlock (AL) allows specimens and tools to be inserted or removed during MSG operations with limited environmental exchange between the WV and the ISS cabin. The MSG facility will also accommodate minor repair/servicing of hardware requiring a clean and/or an encapsulated working environment (e.g. the Fluid Science Laboratory's investigation containers).

Equipment Design↗
PubMed1987

Pulmonary and systemic contribution to canine tracheobronchial blood flow.

To investigate the quantity and pathophysiological relationship of pulmonary and bronchial artery supply to the tracheobronchial tree in dogs in absence and in presence of increased tissue metabolic requirements, pulmonary and bronchial blood flow to the trachea and bronchi was determined by the radioactive microsphere method in nine adult mongrel dogs. Microspheres were injected into the right atrium of three dogs (pulmonary injection group) and into the left ventricle of four dogs (systemic injection group) just before and three, eight and fourteen days after resection and anastomosis of the right main bronchus. The remaining two dogs served as controls without surgery. After the fourth injection, the tracheobronchial tree was harvested, divided into segments, and the radioactivity counted in each segment. At baseline the systemic flow to the tracheobronchial tree expressed as percentage of cardiac output was 0.188% +/- 0.121 and the pulmonary blood flow was 0.007% +/- 0.004 (mean +/- S.D.). Three, eight and fourteen days after transection and anastomosis of the right main stem bronchus, the systemic blood flow to the bronchial segments proximal and distal to the anastomosis increased significantly whereas pulmonary blood flow did not change. Depending on the anatomical segment considered the systemic contribution was between 5 and 100 times larger than the pulmonary one, both at baseline and after transection and anastomosis of the right main stem bronchus, but the ratio diminished in more distal segments where pulmonary blood flow was larger. It is concluded that the systemic blood contribution to the canine tracheobronchial tree is larger than the pulmonary one and that, in the presence of increased metabolic needs, it responds more promptly with increased blood flow.

Animals↗