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Biomedical subjects

A Sebastiani

Publications and source records attributed to A Sebastiani.

At least 91 records · Page 5Linked to original sources

Recurrent central retinal vein occlusion in a young thrombophilic patient with factor V Leiden mutation.

PURPOSE: To investigate the cause of recurrent central retinal vein occlusion in a 26-year-old white woman. METHODS: Case report. Complete blood analyses were done, including HLA tissue typing, immunoserologic and coagulation tests, with cardiovascular and capillaroscopy investigations. Factor V:R506Q and prothrombin 20210 GIA mutations were checked by polymerase chain reaction and restriction enzyme analysis. RESULTS: DNA analysis showed the patient to be heterozygous for factor V:R506Q mutation. During a follow-up of 18-months, after starting anticoagulant therapy, the patient had not suffered from any other ocular or systemic occlusive vascular accident. CONCLUSIONS: The R506Q factor V gene mutation may be associated with recurrent central retinal vein occlusions. Genetic investigation should be promptly recommended in thrombotic patients to establish a specific preventive treatment.

Adult↗

[Determination of hemagglutination inhibiting antibodies against influenza virus A/Port Chalmers/1/73 in samples from the Roman population (1962-1974). Relation of antibody titers to those obtained against previous influenza A strains].

The h.i.a. titer has been determined against the strain of the A/Port Chalmers/1/73 influenza virus in 805 serum samples obtained in Rome from as many adults during six distinct periods between spring 1962 and summer-autumn 1974.

Adolescent↗