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A Seidlová

Publications and source records attributed to A Seidlová.

8 recordsLinked to original sources

Composition of cellular fatty acids in unidentified non-pathogenic corynebacteria.

The composition of fatty acids in lipids of selected strains of non-pathogenic unidentified corynebacteria was determined with the aim to employ such determinations for their characterization. Four strains were characterized by the presence of branched iso- and anteiso-acids. One strain corresponded according to its composition to mycobacteria and nocardiae.

Corynebacterium↗

Small wild rodents rabies in Czechoslovakia.

During a period of 1969-1979 a total of 3174 small wild rodents of the genus Muridae and Microtinae (predominantly Microtus arvalis) were examined. The animals were trapped in five localities differing both in type of ecological conditions and epizootologic situation. Fox-rabies occurred here either enzootically, or epizootologically, or had been completely absent for many years in one of the localities investigated. Of the 71 isolated strains of RV 18 strains were isolated from brain, 25 from brown fat and 28 from salivary glands. Simultaneous isolation positivity in more than one tissue was sporadic. Virus isolations from deep-frozen material were mostly unsuccessful. Basic biological characteristics were determined in each isolate. The isolated strains differed in the rate of adaptation on albino mice and in intracerebral virulence. All isolates exhibited extraneural pathogenicity for common laboratory animals, dogs and foxes, showed distinct viscerotropism, stimulated formation of interferon and produced various forms of non-lethal infection. Incidence of "murine" rabies did not show any locality-specific differences and in longitudinally studied areas was enzootic. In a number of Czech districts there was observed a distinct relationship between fox-rabies incidence and the density of small game animal populations. Role of small wild rodents in the epizootology and epidemiology of rabies is discussed.

Animal Population Groups↗

Enterotoxigenic E. coli in humans.

E. coli strains isolated from persons having diarrhoeal disease were tested for the production of TS enterotoxin. The production of TSE was demonstrated in 2.5% in a series of 80 strains isolated from children under one year of age, having acute diarrhoea. TSE was produced by 8.4% of E. coli strains out of 59 strains isolated from patients over one year of age. Among these strains, an interesting E. coli strain was isolated from the patient T. J., which produced TSE for more than 15 months. The production of TLE was tested though not proved in all strains by experiment on an isolated intestinal loop of an adult rabbit. The test on suckling mice so far appears to be the most suitable test for the demonstration of TSE. The results were considered positive when the index (the ratio of the weight of the whole intestine to the weight of the rest of the body) was higher than 0.08 while indices up to 0.078 were considered negative. E. coli strains with indices of intermediate values and strains with temporary production of TSE, occurring particularly in very small children, deserve special attention. The height of the indices was not influenced by a 30-minute exposure at 60 degrees C, but a decrease in the values of the indices was observed after boiling for a period of 15 min. The occurrence of E. coli strains producing TSE is evidently small in humans in European countries but, without doubt, they are important in the aetiology of diarrhoeal diseases.

Animals↗