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Biomedical subjects

A Sevcík

Publications and source records attributed to A Sevcík.

7 recordsLinked to original sources
PubMed1997

[Analysis of development of hip joint dysplasia in dogs].

Hip joint dysplasia in dogs occurs mainly in large and heavy breeds. It brings about changes on the acetabulum (socket) and the head of thigh bone, thus causing pain, tiredness, refusal to jump and refusal of increased activity. Even though presently the genetic basis of development of this disease, numerous literary sources indicate existence of pre-disposing factors that facilitate development in later stages of life. Diet and unbalanced development of skeleton and support tissues-ligaments, joint capsule and musculature also have the effect on development of dysplasia. We have analyzed acquired results of X-ray examination of dogs-German shepherds. The size of the group was 4 206 and the examination was aimed at incidence of hip-joint dysplasia during the period of 1977-1995 in the Slovak Republic. We have found out that in 1977 there were 70.7% positive cases out of the total number of examined individuals. Gradual exclusion of dogs with heavier grades of dysplasia (D, E) decreased occurrence of dysplasia to current rate of 40.8%. We considered it to be a high incidence rate. Internal structure of the positive group has changed. The number of dogs with the lightest grade of dysplasia (B) has increased, while the number of heavier grade dysplasia (C, D, E) decreased. In other breeds of dogs, of which more than 20 have been examined at the clinic, the following results have been acquired: Slovak chuvash-32%, Bavarian and Hannover bloodhound-30.6%, Rotweiler-28.6%, Newfoundland dog-26.3%, Bern sheep-dog-13.6%. At the same time we analyze the incidence of dysplasia in dogs whose parents were negative. Group of descendants of 11 negative males and 28 females consisted of 73 dogs. Through x-ray examination, 42.5% of dogs were found to have dysplasia B, C and D at the age of 1 year.

Animals↗
PubMed1996

[Complications during myelographic examination in dogs].

The occurrence of spinal disease in dogs is quite frequent. Clinical examination and survey radiography do not allow to make an exact diagnosis in many cases. Therefore the radiographic method-myelograhy is used to make an exact diagnosis and to locate the pathological process in the spinal cord. Myelography can be accompanied by some complications caused by a contrast medium of anaesthesia. In this study, the occurrence of complications was evaluated when the contrast medium Dimer X and three types of general anaesthesia were used: xylazine-ketamine, chlorpromazine-piritramide, chlorpromazine-pentobarbital. Certain relations between the origin of complications, dog weight and total time of anaesthesia are indicated. The results obtained show that the highest number of cases with complicated regeneration was observed after the use of the combination xylazine-ketamine when the average duration of anesthesia was 31.1 minutes comparing to the combination chlorpromazine-pentobarbitale with average duration of anaesthesia was 127.7 minutes with the lowest number of complications. We also refer to certain relations between weight and the occurrence of complications where the highest correlation (r = 0.59) was recorded for xylazine-ketamine anaesthesia. The correlation coefficient (r = 0.27) for chlorpromazine-pentobarbital documents very low correlations of the followed values.

Animals↗
PubMed1995

[Desmoids: are there any new developments?].

In the submitted review of the literature the authors evaluate contemporary therapeutic possibilities of mesenterial desmoids. A more detailed pattern of cytotoxic and non-cytotoxic chemotherapy, actinotherapy and hormonal therapy is presented. Surgical resection is limited by the size of the tumour and above all by early detection before the size of 15 cm is reached. In larger tumours conservative treatment by a combination of non-cytotoxic and hormonal treatment is better. Actinotherapy of the intraabdominal region is not suitable. The percentage of relapses is high, a standard therapeutic procedure has not been elaborated so far. Despite rather surprising remissions of desmoids in individual cases the general results of different groups are not encouraging. In a case-history the authors describe their experience with the treatment of a young female patient with a mesenterial desmoid which, however, was not successful.

Adult↗
PubMed1990

[Changes in blood levels of progesterone, triiodothyronine and thyroxine and the results of quantitative histological analysis of the placentoma and corpus luteum in cows after prolonged labor].

Changes in the cell structure of the placentoma and the corpus luteum were subjected to quantitative histological investigation, parallel with the examination of the concentrations of progesterone (P4), triiodotyronine (T3) and tyroxin (T4) during parturition (Oth hour) and two and six hours after parturition. The hormone concentrations were determined by the RIA method. The results of the quantitative histological analysis of the placentomae and the corpus luteum suggest that when the placenta is retained there is a significantly higher number of maintained epithelial cells in the placentoma crypts and a higher number of unchanged small, dark and large, light lutein serraetion cells in the biopsy of the corpus luteum during the period under investigation. The morphological finding significantly correlates with higher concentrations of P4 in the blood of the cows with retained placenta, as compared with those whose placenta was not retained. It can be derived from the pattern of changes in T3 and T4 concentrations, compared with P4 and with the histological finding, that there is a functional relationship between the placentoma, corpus luteum, and the thyroid gland.

Animals↗
PubMed1976

[Fixed acids during the traditional cesarean section in cows].

The values of lactic acid, pyruvic acid and L/P index were studied in cows at the traditional Caesarean section. The values of the mentioned metabolites are presented in dependence on the intensity and length of parturient activity that are affected by the anesthesia applied during surgical procedures. An increase of the level of lactic acid was hindered by the anesthesia at the protracted parturient activity. An unequal drop of the level of lactic acid resulted from the interrupted intensive parturient activity and lowered labor of the organisms due to anesthesia during the surgical procedure. The levels of pyruvic acid increase after the anesthetic applied, but already during the surgical procedure a drop of their levels occurs that continues, with certain fluctuations, for 48 hours after the fetus extraction. The L/P index is relevant to the levels of fixed acids that reflect the labor of the organism at the protracted parturient activity and under an oxygen deficit. The increased L/P index after the application of the anesthetic decreases for three hours after the surgical procedure and later on, it maintains approximately the same level.

Animals↗
PubMed1976

[Changes of lactic and pyramic acid levels and of the L/P index in cows and calves during parturition].

The levels of lactic acid, pyruvic acid and L/P index were studied during parturition in cows and calves. The results demonstrate various values of the metabolites studied in dependence on the length of parturient activity and on the way of finishing the parturition. The level of lactic acid increases with protracted parturient activity and that of puruvic acid decreases. Anesthesia applied at the traditional caesarean section hinders the course of fixed acids, which is reflected in the values of the L/P index. An excessive accumulation of fixed acids in mother's organism at the protracted parturition unfavorably influences the metabolism of fetus by means of the fetoplacental bed. Anesthesia does not affect the levels of the metabolites studied in calves. The values of the L/P index are in the same proportion as the levels of lactic and pyruvic acids are.

Animals↗