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A Sheen

Publications and source records attributed to A Sheen.

7 recordsLinked to original sources

Evaluation of calibration of spirometers.

The accuracy of 15 spirometers was evaluated with a commercially available calibrator. Nine spirometers were found to be within limits recommended by the manufacturer of the calibrator for forced vital capacity; eight were within recommended limits for FEV1. The calibrator is a convenient instrument for rapid evaluation of the accuracy of spirometers.

Calibration↗

Simultaneous use of rapidly absorbed and sustained release theophylline preparations in children.

Each of 12 asthmatic children received a single dose of Theolair, 5 mg/kg, a single dose of Theolair SR, 10 mg/Kg, or both Theolair, 3 mg/Kg and Theolair SR, 10 mg/Kg on three separate days. Administration of both preparations together was followed by serum theophylline concentrations significantly higher than Theolair alone at 2 or 12 hours and significantly higher than Theolair SR alone at every time except six hours. This method of theophylline administration may be useful in the asthmatic patient who requires medication only intermittently.

Absorption↗

Comparison of Theolair SR and Theo-Dur tablets.

The effects of administration of single doses of 10 mg/kg of two sustained release theophylline preparations were compared in a double-blind, crossover study in eight asthmatic children. Serum theophylline concentrations were maintained well for 8-10 hours after administration of Theolair SR and 10 and 12 hours after administration of single doses of Theo-Dur.

Absorption↗

Serum theophylline concentrations in asthmatic children.

Serum theophylline concentrations measured in 25 asthmatic children for whom continual therapy had been prescribed were found to exceed 8 mcg/ml more often in those receiving sustained-release theophylline preparations than those receiving short-acting theophylline preparations.

Adolescent↗