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Biomedical subjects

A Shelley

Publications and source records attributed to A Shelley.

7 recordsLinked to original sources
PubMed2001

Case study of an anxious child with extensive caries treated in general dental practice: financial viability under the terms of the UK National Health Service.

This case study describes the management of Callum, an anxious 7-year-old boy with extensive caries. Callum's dental care was carried out in a general dental practice in the North of England under the terms of the National Health Service. A preventive programme was carried out in conjunction with the restorative philosophy according to guidelines published by the Dental Practice Board in 1997.

Capitation Fee↗
PubMed2000

Associated deficits in mismatch negativity generation and tone matching in schizophrenia.

OBJECTIVE: Schizophrenia is associated with deficits in mismatch negativity (MMN) generation and in the ability to match two tones following brief delay. Both deficits reflect impaired early cortical processing of auditory information. However, the relationship between deficits in MMN generation and tone matching performance in schizophrenia has not been established. METHODS: MMN and tone matching performance was evaluated in 12 schizophrenic subjects and 12 similar aged controls. A pitch separation known to produce non-ceiling performance in patients (5% Deltaf) was used. Narrow band filtering of MMN data was used to enhance signal-to-noise ratio. RESULTS: Schizophrenic subjects showed impairments in both MMN generation and tone matching performance. The two deficits were significantly correlated across subjects. In addition, decreased MMN amplitude and poorer tone matching performance correlated with increased severity of negative symptoms. CONCLUSIONS: These findings support the concept that similar neurophysiological mechanisms underlie MMN and tone matching deficits in schizophrenia. Further, they indicate that increased sensitivity to environmental change may be related to social withdrawal and other negative symptoms in schizophrenia.

Acoustic Stimulation↗
PubMed1992

School nurses: constraints and opportunities for the future.

School nurses are all too often the forgotten element of the school health services, lacking in central guidance and with a great variety of duties and functions which have grown up in an ad hoc and unstructured way. At a time when many districts are reviewing their approach to these services in the light of current policy changes, it would be helpful to step back and consider the issues from a historical perspective in order to understand the great variability in the role of school nurses today. Changing management structures demand improved understanding and acceptance of review and evaluation mechanisms, but where basic information is lacking, overall considerations of need and effectiveness may be severely limited.

Forecasting↗
PubMed1991

The Breast Clinic at Ga-Rankuwa Hospital/MEDUNSA.

The Breast Clinic at Ga-Rankuwa Hospital/MEDUNSA serves a large population of black South Africans. The patients present at a young age and commonly with very advanced disease. Problems in follow-up are more complex in this group because of difficulties with finance, transport and communication. The very large number of cases lost to follow-up and regular supervision after completion of treatment militates against collecting data for accurate reporting of results. An account is given of our experience in dealing with 532 cases of breast carcinoma seen over a period of 6 years.

Adult↗
PubMed1976

Further evidence for the transmission of Mansonella ozzardi by Simulium amazonicum in Brazil.

The transmission of Mansonella ozzardi was studied in two rubber collecting villages on the River Purus, state of Amazonas, Brazil. Haematophagous insects were collected from human and bovine baits during the day and night: 687 Mansonia amazonensis and 154 Culicoides sp. indet. were free from infection with M. ozzardi. The former species is probably not a vector, but the low numbers of culicoides dissected preclude any determination of its vector status. Thirty-five (0-99%) of 3530 Simulium amazonicum dissected were found naturally infected with larvae of M. ozzardi. Two hundred and ninety-nine M. amazonensis and 280 S. amazonicum were experimentally infected with M. ozzardi by feeding on volunteers. Microfilariae were detected in the blood meals of both species but no developing larvae were found in the thoracic muscles of M. amazonensis, confirming its non-vector status; 7-1% of the S. amazonicum dissected had filarial larvae in the thorax. There was a statistically significant difference between this rate and the natural rate of infection in this region, verifying that penetration of the thoraric muscles by M. ozzardi had occurred in the experimental infection. The data confirm the observation of Cerqueira (1959) that S. amazonicum transmits M. ozzardi in Brazil.

Animals↗