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Biomedical subjects

A Shostak

Publications and source records attributed to A Shostak.

41 records · Page 3Linked to original sources
PubMed1979

Normalized thyroxine as a screening test for hypothyroidism in full-term and preterm newborn babies.

Thyroid function was assessed in full-term and preterm newborn babies by serum thyroxine (T4), normalized thyroxine (T4N) and thyroid-stimulating hormone (TSH) assays. At age 24 h, there was a significant difference in T4 and TSH values between the full-term and preterm groups; no such difference was found in the T4N values. By 21 days of age, the TSH values were still significantly higher in full-term babies compared with preterm ones, but the T4 values were similar. The T4, T4N and TSH values at 24 h in preterm newborns with respiratory distress syndrome were similar to those in normal preterm babies, and the changes in these values with age had no consistent pattern. In preterm babies with low 24-h T4 and T4N values, these two parameters increased with age, reaching normal adult values by 21 days. We concluded that T4N could serve as a useful thyroid function test in the newborn.

Female↗
PubMedDate not supplied

Splanchnic volume, not flow rate, determines peritoneal permeability.

To distinguish the effects of splanchnic blood flow rate from those of splanchnic volume on peritoneal transfer rates, measurements were made in rabbits before and after intraperitoneal exposure to sodium chromate. The sodium chromate induced reversible hepatic sinusoidal block with consequent portal venous congestion and stasis, which was demonstrable on histologic sections. Concurrently the ultrafiltration rate, and ultrafiltration coefficient each doubled after chromium even though the dialysate reabsorptive rate increased and the absorptive diffusion of glucose was at least as high as in control dialyses. Chromium induced significant increases in mass transfer coefficients of urea, potassium and phosphate and in protein clearance. These data suggest that splanchnic volume is an important determinant of peritoneal transfer functions and that the hepatic capillaries may contribute appreciably to transfer ordinarily ascribed to peritoneal capillaries alone.

Animals↗