PubMed Health⌕ Search

Biomedical subjects

A Simard

Publications and source records attributed to A Simard.

61 records · Page 4Linked to original sources

Vitamin D deficiency and cancer of the breast: an unprovocative ecological hypothesis.

It has been stated recently that atmospheric acid haze containing sulfur dioxide and sulfate crystals may lead to vitamin D deficiencies in exposed populations and increase breast cancer mortality, especially in Montréal. In view of the implications of this hypothesis, we have done a case-control study within the same cohort of women attending the Canadian National Breast Screening Study to check whether a depletion of vitamin D could be detected in the diet of breast cancer patients (n = 108) as compared to controls (n = 322) or a random sample of 1,141 women in our Montréal centre as well as 40 breast cancer cases for which precise food intake data were available by way of a 24-hour dietary journal. The mean daily intake of vitamin D of breast cancer cases was 1.65 +/- 2.48 I.U./kg while in 322 controls matched for age the mean intake was 1.34 +/- 1.17 (S.D.). It has to be pointed out that in the 5 years before diagnosis, cancer patients had not increased significantly their consumption of foods rich in vitamin D, namely milk, cheese, yoghurt, butter and fish. It has also to be stressed that, in relation to the recommended daily intake, twice as many breast cancer patients than controls had a higher consumption of vitamin D.

Adult↗

The National Breast Screening Study: pre-recruitment sources of awareness in participants.

Data collected by questionnaire from 89,835 women on entry into 15 Canadian National Breast Screening Study (NBSS) centres reveal pre-recruitment sources of awareness: radio and television were reported by 30%; workplace 6%; friends 35%; physician 6%; and other by 23% of respondents. Personalized letters of invitation employed in 5 centres were an important source of awareness. In the age group recruited, 40-59 years, age had no influence on the source reported. However women with post-secondary school education were less likely to report radio and television as a source and more likely to report newspapers compared to women with less education. Women with only public school education were less likely to report the workplace as a source of awareness than women with post-secondary education. Recruitment strategies for screening programs may be more successful if publicity on radio and television is geared to women of lower educational status and if publicity in newspapers is geared to women of higher educational status, supplementing both with personalized letters of invitation.

Adult↗

[Over-estimation of incidence in the Quebec Tumor Registry 1981-1982].

Since 1981, the Quebec Tumor Registry (FTQ) is using form AH-101P which is filled out for all patients seeking care in Quebec hospitals. From a list of 8,000 names in 1981-82, we have found that 4.8% was constituted of cases reported 2, 3 and 4 times. In two major hospitals, we have checked 71 medical records of patients reported more than once to FTQ using the AH-101P form with what was found in the hospital records. Only 6 multiple cancers (8.5%) were found. All other cases were constituted of invasions, infiltrations or metastasis. It is concluded that, despite the new procedure, cancer incidence is still overestimated in FTQ in 1981-82 but this problem should disappear in the near future.

Hospital Records↗