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Biomedical subjects

A Sinnott

Publications and source records attributed to A Sinnott.

4 recordsLinked to original sources
PubMed2003

Use of the NeuroMate stereotactic robot in a frameless mode for movement disorder surgery.

BACKGROUND/AIMS: To evaluate the use of the NeuroMate stereotactic robot with a novel ultrasound registration system for movement disorder surgery (MDS). METHODS: Using the robot in a frameless mode, 51 patients underwent MDS. Surgical planning was carried out using MRI data obtained more than 24 h before surgery. RESULTS: 37 out of 50 targets in the subthalamic nucleus were satisfactorily identified with a single microelectrode trajectory and the final electrode positions were at a mean distance of 1.7 mm from the calculated target. There was a significant improvement in motor scores of the Unified Parkinson's Disease Rating Scale III (off medication) at 6 (43%) and 18 months (51.7%) compared to pre-operative scores (p < 0.05). CONCLUSIONS: The frameless robot using only MRI data can be used for MDS. The temporal separation of imaging from the surgical procedure provides additional time for detailed image analysis and planning.

Humans↗
PubMed1983

Psychological alternatives to long-term benzodiazepine use.

The aim of the study was to evaluate the effectiveness of psychological management of anxiety as an alternative to long-term benzodiazepine medication. Fifty patients were identified who had been taking benzodiazepines continuously for at least one year. No significant differences were found between patients who joined a treatment group and patients who were simply advised by letter to cut down their pills. Patients gave a variety of reasons for initially requiring medication and somewhat different reasons for needing to maintain chemotherapy, which suggested that pill-taking might be self-maintaining through withdrawal symptoms.

Adult↗
PubMed1981

Agoraphobia: a situational analysis.

Examined previous notions about the nature of agoraphobia. A contrast of emphasis was found between those who regarded it primarily as a situational fear and others who saw it essentially as a product of some underlying anxiety. A more precise situational analysis was attempted that focused on six variables: Unaccompanied vs. with someone, distance from home, familiarity of location, crowdedness, type of location, and time spent. One hundred and twenty-eight situation descriptions were generated by factorially combining the different levels of each variable. The items thus produced were assembled randomly into a questionnaire that was completed by 30 agoraphobic patients. The importance of the contribution of each variable to the rated fear-provoking potential of the situation description was analyzed. Results were discussed in terms of the agoraphobic as typically dependent upon a significant other, and treatment implications were examined.

Adult↗