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Biomedical subjects

A Sion

Publications and source records attributed to A Sion.

16 recordsLinked to original sources

Efficacy of argon laser irradiation in removing intracanal debris.

Endodontic instrumentation, irrigation, or intracanal medication are unable to totally remove intracanal debris. The purpose of this study was to evaluate the efficacy of argon laser irradiation in removing debris from the root canal system. After cleaning and shaping, 12 single rooted teeth were randomly divided into two groups of six teeth each. The first group, which served as the control, was not lased. In the second group, a 300 microns argon laser fiber optic was introduced into the root canal of each tooth, to its working length. Fifteen pulses of 100 msec each with an energy of 2 watts were delivered for 5 seconds at the apex. The lasing procedure was repeated at 1 mm intervals along the root canal, and the fiber tip was retrieved from the apex to the orifice. Computerized scanning electron microscopy analysis revealed that the amount of debris in the lased group was significantly lower than that in the control (p = 0.0001). On the basis of these results, it appeared that intracanal argon laser irradiation was an efficient mean of removing intracanal debris.

Argon↗

Intraligamentary injection of slow-release methylprednisolone for the prevention of pain after endodontic treatment.

The intraligamentary injection of a slow-release steroidal, the anti-inflammatory agent slow-release methylprednisolone (Depomedrol), was compared to a placebo and to an active placebo (Mepivacaine) in preventing postoperative pain after root canal treatment. The results clearly demonstrated that the tested drug significantly reduced the frequency and intensity of postoperative pain sequelae in the experimental set-up.

Adult↗

Chronic tophaceous gout. A case report.

A review of gout is presented, followed by a discussion of the current medical literature on diagnosis, differential diagnosis, staging, and treatment. Chronic tophaceous gout is not as prevalent as it once was because of early diagnosis and treatment, but it is still encountered in the podiatric practice. A severe case of chronic tophaceous gout is presented. The patient was successfully treated by surgical intervention. Although surgery may be avoided in most cases, it is indicated when intractable pain, loss of motion, and massive joint destruction are present.

Chronic Disease↗

Mechanistic aspects of paraquat toxicity in E. coli. A spin trapping study.

Mechanistic aspects of paraquat monocation radical (PQ.+) and copper involvement in paraquat toxicity have been examined using E. coli B cells. Electron spin resonance (ESR) spectrometry combined with cell survival studies were used to explore the correlation between radical production and biological damage. The line broadening agent oxalato-chromiate (CrOx) was used to characterize the anoxic partition of PQ.+ inside and outside the cell. In the presence of CrOx the ESR signal was totally eliminated, indicating that intracellular species were undetectable and that, contrary to previous reports, PQ.+ exclusively accumulates outside the cell. The PQ.+ radical does not react with H2O2 but disappears in the presence of H2O2 when catalytic traces of Cu(II) are present. Spin-trapping studies using DMPO showed that in aerobic environment paraquat-induced O2 radicals are detectable exclusively in the extracellular compartment. The correlation between PQ.+ appearance and the biological damage is not simple. PQ.+ non-toxically accumulates, in the absence of oxygen and either Cu(II) or H2O2. By contrast, with both H2O2 and Cu(II) the cells are rapidly killed but PQ.+ was undetectable. These results reconfirm the key catalytic mediatory function of transition metals in paraquat toxicity.

Aerobiosis↗

Incidence of pulmonary embolism.

During the last 5 years in a community hospital of 219 beds, the most common cause of death (primary and secondary or contributory) was pulmonary embolus. In the US fatal pulmonary emboli occur in 5 patients for 1,000 inpatients, nonfatal pulmonary embolism in 20 patients per 1,000 inpatients, about 142,000 patients suffer fatal pulmonary emboli and 568,000 suffer nonfatal pulmonary emboli each year. In 422 autopsies 93 patients (21%) have pulmonary emboli undiagnosed during the patient's life time. In comparing with other statistical studies, about 21% represent the death rate of patients treated for pulmonary emboli if the diagnosis is previously made. On the basis of this observation the incidence of pulmonary emboli and thrombosis of the lower limbs appears to be about the same in community and the university hospitals, disregarding if the patients are having the highly skill care or are treated by the general practitioner without the sophistication of expensive technology.

Adult↗

"Narcotic" Lung.

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Adult↗