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Biomedical subjects

A Sklovský

Publications and source records attributed to A Sklovský.

At least 19 recordsLinked to original sources
PubMed1991

Lipid metabolism in young males with hypotestosteronaemia and oligospermia prior to, during, and after treatment.

Relationships between plasma testosterone levels and selected parameters of lipid metabolism were studied in a group of young sterile males prior to, during, and after hormone therapy. Initial hypertriacylglycerolaemia and decreased concentrations of HDL cholesterol returned to normal values after 30 days of methyltestosterone administration. LDL cholesterol concentrations decreased significantly as did plasma apolipoprotein B levels. These changes persisted also one month after cessation of treatment. The results suggest that restoration of initially decreased testosterone levels in the studied group of sterile males is associated with the restoration of the lipid profile.

Adult↗
PubMed1989

Some measures of lipid metabolism in young sterile males before and after testosterone treatment.

The concentration of total cholesterol and triacylglycerols in plasma and their distribution in lipoproteins as well as the level of apolipoprotein-B and of endogenous testosterone were measured in 30 young sterile males before and after the treatment with methyltestosterone (Agovirin SPOFA) in a dose of 10 mg daily for 30 days. Before the treatment the level of total cholesterol in plasma and in VLDL fraction was normal, while that in LDL fraction was increased and in HDL fraction decreased. Similarly, the level of triacylglycerols in plasma was increased and correspondingly also the levels of that in all lipoprotein fractions. After the treatment no changes in total and VLDL cholesterol were found, while a significant decrease in LDL fraction and increase in HDL fraction was observed. Moreover, a significant decrease was found in a level of total plasma and VLDL triacylglycerols.

Adult↗