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A Small

Publications and source records attributed to A Small.

At least 19 recordsLinked to original sources
PubMed2006

Presence of Salmonella in the red meat abattoir lairage after routine cleansing and disinfection and on carcasses.

Foodborne pathogens, such as Salmonella, may remain in abattoir lairages after cleansing and pose a risk of transfer and contamination from one processing day to the next. These organisms may be transferred to the outer surface of animals held in lairage facilities, and the skin or hide may be a significant source of microbial contamination on the red meat carcasses subsequently produced. Sponge samples were taken from various sites in the lairage (n = 556), and single-pass sponge samples were taken from one side of red meat carcasses (n = 1,050) at five commercial abattoirs in Southwest England and tested for the presence of Salmonella. Of these, 6.5% of lairage samples were positive, containing estimated numbers of up to 10(4) Salmonella organisms per sampled area (50 by 50 cm). Salmonella was found on 9.6% of 240 lamb carcasses, 12.7% of 330 beef carcasses, 31% of 70 pig carcasses, 20% of 80 calf carcasses younger than 14 days of age, and none of 330 cull cow and bull carcasses. Subtyping divided the 137 isolates into seven serogroups and three pulsed-field gel electrophoresis clusters, and sensitivity testing against a bank of 16 antimicrobials indicated that 47 isolates had resistance to one or more antimicrobial agents. These results indicate that Salmonella contamination can persist in the lairage environment from one processing day to the next and that Salmonella is present on red meat carcasses, although the implications of residual lairage contamination on carcass meat microbiology are not clear from this study. Abattoir owners should take steps to reduce the level of contamination in their premises to prevent contamination from being carried over from one processing day to the next.

Abattoirs↗
PubMed2004

Spread of marker bacteria from the hides of cattle in a simulated livestock market and at an abattoir.

The spread of microbial contamination on the hides of beef was investigated at two stages in the meat chain: (i) in a simulated livestock market ("the market") using 33 animals, and (ii) in the unloading-to-skinning area of a commercial abattoir using 18 animals. At both stages, harmless bacterial markers (nalidixic acid-resistant Escherichia coli K-12; rifampicin- and nalidixic acid-resistant Pseudomonas fluorescens; and a tetracycline-resistant E. coli) were inoculated on the hides of a small number of selected animals, and their transfer to other animals and the environment was examined. At the market, the initial prevalence of animals positive for the hide markers (9.1% in each phase) introduced in the presale pen, sale ring, and postsale pen changed to 39.4, 15.1, and 54.5%, respectively, by the end of the market process. In addition, widespread contamination of the market environment with the hide markers was observed. At the abattoir, the initial prevalence of animals positive for the hide marker (11.1%) inoculated at unloading increased to 100% (hide before skinning) and 88.8% (skinned carcass). In addition, another marker inoculated on environmental surfaces in lairage pens, races, and stunning box was detected on 83.3% (hide before skinning) and 88.8% (skinned carcass). These results, although obtained with a relatively small number of animals, demonstrate that both the livestock market process and the unloading-to-skinning process at abattoirs can facilitate the extensive spread of microbial contamination on hides not just within, but also between, batches of animals.

Abattoirs↗
PubMed2003

Conditions in lairages at abattoirs for ruminants in southwest England and in vitro survival of Escherichia coli O157, Salmonella Kedougou, and Campylobacter jejuni on lairage-related substrates.

Information on lairages (regarding design, construction materials, and use of bedding and cleaning regimes) was collected for 21 commercial cattle and/or sheep abattoirs in southwest England. Overall, roughened or grooved concrete was the most common lairage flooring material. Straw bedding was used in the majority of lairages and was changed between animal batches, daily, weekly, and monthly in roughly 5, 60, 15, and 10%, respectively, of the surveyed lairages. Lairages were commonly washed with cold water with no detergents and/or disinfectants, and only about half the lairages were washed daily. Also, a three-pathogen cocktail inoculum comprising Escherichia coli O157 (NCTC 12900), Salmonella Kedougou (VLA S488/01), and Campylobacter jejuni (VLA C4) (at 8, 8, and 7 log CFU/ml or 8, 8, and 7 log CFU/g, respectively) was suspended in either broth (for nonfecal contamination) or bovine feces (for fecal contamination). Samples of the four most common substrates present in lairages (concrete, straw, metal, and hide) were contaminated in vitro with either fecal or nonfecal inocula and subsequently held in the laboratory at 10 or 25 degrees C for 1 week. Bacterial counts for these samples were monitored daily and used to assess the number of days required for a 90% reduction of each pathogen population. In most cases, pathogens survived for >1 week, with survival rates being higher for straw or hide than for concrete or metal and higher for fecal contamination than for nonfecal contamination. Overall, if survival rates for the three pathogens under practical lairage conditions were similar to the in vitro survival rates found in this study, contamination of lairages with pathogens could be carried over from one batch of animals to another and/or from one day to the next.

Abattoirs↗
PubMed2002

Potential for the spread of Escherichia coli O157, Salmonella, and Campylobacter in the lairage environment at abattoirs.

Prevalences of Escherichia coli O157, Salmonella spp., and Campylobacter spp. were examined in 270 swabs taken from selected sites along the unloading-to-slaughter routes of animal movement in lairages of six commercial abattoirs, three for cattle and three for sheep. The overall prevalences of the pathogens in the respective lairage environments were compared with those for 270 swabs from the pelts of 90 lambs examined in the present study and 270 swabs from the hides of 90 cattle examined in a previous study that were slaughtered at the same abattoirs on the same days. Also, the results obtained were analyzed with the aim of identifying critical points at which animal-environment-animal transfer of the pathogens in lairages occurs. The results showed that (i) the overall prevalences of E. coli O157, Salmonella spp., and Campylobacter spp. were 27.2, 6.1, and 1.1%, respectively, in cattle lairages and 2.2, 1.1, and 5.6%, respectively, in sheep lairages; (ii) the overall prevalences of the three pathogens on cow hides (28.8, 17.7, and 0%, respectively) and sheep pelts (5.5, 7.8, and 0%, respectively) were higher than the overall prevalences in the respective lairage environments; (iii) the most frequently contaminated sites in cattle lairages were holding pen floors (50% of swabs positive for one or more pathogens), entrance gates of stun boxes (27.8% of swabs positive for one or more pathogens), and stun box floors (22.2% of swabs positive for one or more pathogens); (iv) the most frequently contaminated sites in sheep lairages were unloading ramp floors, holding pen floors, and water troughs (33.3, 22.2, and 22.2%, respectively); and (v) overall, cattle lairages and cow hides were more frequently contaminated with the pathogens than were lamb lairages and lamb pelts. Further research is needed to develop strategies for the incorporation of pathogen control in lairages into integrated microbial meat safety systems.

Abattoirs↗
PubMed2002

Pulsed-field gel electrophoresis characterization of Shiga toxin-producing Escherichia coli O157 from hides of cattle at slaughter.

Contamination of the brisket areas of the hides of healthy adult cattle with Shiga toxin-producing Escherichia coli O157 at slaughter in England was studied. In total, 73 cattle consignments comprising 584 animals delivered to one abattoir over 3 days during 1 week in July 2001 were studied: 26 cattle consignments arriving on Monday, 32 consignments arriving on Wednesday, and 15 consignments arriving on Friday. Consignment sizes ranged from 1 to 23 animals, with a mean consignment size of 8. The hide of the first animal to be slaughtered in each consignment was sampled by using a sponge swab moistened with 0.85% saline to rub an unmeasured brisket (ventral) area (ca. 30 by 30 cm). The process of isolating E. coli O157 from the swabs consisted of enrichment, screening with immunoprecipitation assay kits, and immunomagnetic separation. E. coli O157 was found on 24 of 73 (32.9%) cattle hides examined, and 21 of these 24 isolates produced Shiga toxins. The 24 E. coli O157 isolates produced six different pulsed-field gel electrophoresis profiles, and 18 (75%) of the isolates were of one prevalent clone. The high prevalence of one E. coli O157 clone on the hides of cattle at slaughter could be due to a high prevalence of that clone on the 18 farms involved (not investigated in the current study), in the postfarm transport or lairage environments, or both. Since the lairage environment, but not the farm of origin or the postfarm transport vehicle, was a factor common to all 18 cattle consignments, it could have played an important role in spreading the prevalent E. coli O157 clone to the cattle hides. Lairage pen floors and the stunning box floor were identified as the most probable sites along the unloading-to-slaughter route at which the brisket areas of cattle hides could become contaminated.

Abattoirs↗
PubMed1999

Preferences for participation in treatment decision making and information needs of parents of children with cancer: a pilot study.

This study was performed to obtain information on parents of children with cancer: (a) what role parents preferred to assume in treatment decision making (TDM); (b) parents' priority information needs; (c) if a relationship existed between TDM preferences and information needs; and (d) if sociodemographic, disease and treatment variables predicted TDM preferences or information needs. A cross-sectional survey was conducted with a convenience sample of 58 parents who had a child less than 13 years of age diagnosed with cancer in the previous year. Instruments included a Sociodemographic, Disease, and Treatment Questionnaire; the Control Preferences Scale for Pediatrics, and an Information Needs Questionnaire. The results showed that parents had systematic preferences about TDM, preferring collaborative followed by passive and active roles. Nine priorities in information needs (highest to lowest) were found: (a) treatments and tests, (b) cure, (c) caring for my child, (d) emotional impact, (e) side effects, (f) physical impact, (g) disease, (h) coping with painful procedures, and (i) impact on the family. Sociodemographic, disease and treatment variables were not predictive of preferences for TDM or information needs. Concrete informational needs take precedence over issues of emotional or family impact or pain. A low Kendall's coefficient (0.07) indicated that parents as a group do not have uniform information needs. Information giving must be individualized.

Adult↗
PubMed1999

The effects of slow- and fast-rhythm classical music on progressive cycling to voluntary physical exhaustion.

BACKGROUND: To investigate, based on the parallel information processing model and arousal hypothesis, whether musical tempo and its manipulation during exercise affect the maximal workload (watts) achieved during progressive cycling. METHODS DESIGN: repeated measures experiment that involved one control and four treatment conditions. SETTINGS: the experiment was performed in a controlled laboratory environment. PARTICIPANTS: twenty-four male and female volunteers, recruited from among a University population, were tested. INTERVENTION: the data collection proceeded in five counterbalanced test-sessions that included control (C), slow music (SM), fast music (FM) slow to fast music (SFM) and fast to slow music (FSM) interventions. In the last two conditions, musical tempo was changed when the participant's maximal HR reserve has reached 70%. In all test-sessions, participants started to cycle at 50 watts and then the workload was increased in increments of 25 watts every minute until self-declared exhaustion. Maximal ergometer cycling was defined as the workload at the last completed minute of exercise. MEASURES: workload, HR, and postexperimental ratings of test-session preferences were the dependent measures. RESULTS: Significantly higher workload was accomplished in the SFM condition. No between-session differences were seen in HR. The results also yielded significantly better "efficiency", in terms of workload/HR reserve ratio, in the SFM session. PARTICIPANTS preferred the FM and SFM sessions more than the other sessions. CONCLUSIONS: Switching to FM during progressive exercise results in the accomplishment of more work without proportional changes in HR. These effects may be due to distraction from fatigue and are, apparently, dependent on the attention capturing strength of the distracting stimulus.

Adult↗
PubMed1991

Breast cancer screening among relatives of women with breast cancer.

BACKGROUND: National surveys indicate that only 15% to 30% of all women in the general population 50 years of age or older have an annual mammogram. METHODS: We studied first-degree female relatives of women with breast cancer, who are at elevated risk of disease, to describe the breast cancer screening practices of these relatives and to improve their practices through a program of intensive education. We report here the screening behaviors of 2471 relatives of women with breast cancer. RESULTS: Self-reported behaviors were as follows: 49% performed monthly breast self-examination and 70% had annual breast examinations by a medical professional. Of 983 women 50 years of age or older, 49% had had a mammogram, but only 14% have a mammogram annually. Of women 50 years of age or older who had never had a mammogram, 92% reported never having had one recommended by a medical professional. CONCLUSIONS: Our findings indicate that screening behaviors in relatives of breast cancer patients are not substantially different from those of women in the general population. Enhanced efforts both to educate medical professionals and to encourage women to demand screening mammography are necessary to reduce breast cancer mortality.

Adult↗
PubMed1983

A comparison of self-devaluation and somatic suggestion content in depressive mood manipulation.

The Velten Mood Induction Procedure (VMIP), often used to manipulate depressive mood, has its effectiveness attributed to the self-devaluative content of its statements; this finding supports cognitive theories of depression. Recent research has suggested that somatic content is more important than self-devaluation content in producing depressive mood variations. To study this using the VMIP, a neutral condition and two modified depression conditions were used: Somatic and self-devaluation (N = 302). The results indicate that self-devaluative statements resulted in significantly more depressed affect than neutral Ss, but no more than somatic statements; this latter group, however, did not differ from neutral Ss. The results of the previous research indicating the importance of the somatic suggestion manipulations as having more influence than negative self-evaluative statements is questioned.

Adult↗
PubMed1983

Intellect, perceptual characteristics, and weight gain in anorexia nervosa.

Studied weight gain in a group of primary anorexics by examining two popular psychodiagnostic measures, the Wechsler and Rorschach, for indices that may predict improvement. Twenty-seven successively admitted anorexics to a behavior modification weight gain program at NIMH were studied. Using weight gain as a continuous criterion, multiple regression analyses indicated that perceptual-personality variables did not have any predictive power. Cognitive focusing skills, as measured by the Arithmetic and Digit Span subtests of the Wechsler, were found to account for roughly half of the variance and to be good predictors of weight gain.

Adult↗
PubMed1983

In vitro renal transport of organic ions during exposure to hyperbaric helium.

The possibility that hyperbaric helium can modify membrane function in nonneural cells was investigated by measuring the effect of pressure (29.6 atm He + 1.0 atm O2) on transport of the organic anion p-aminohippurate (PAH) and the organic cation tetraethylammonium (TEA) by renal cortex slices. Control slices were exposed to 100% O2 at 1 ATA. A unique incubating and shaking apparatus was built to allow remote control of the incubation conditions in a sealed chamber containing hyperbaric O2. In rat or rabbit renal tissue incubated for 90 min, pressure did not affect the uptake of either substance and was without effect on the total water content and inulin space of rat renal cortex. The kinetic characteristics of the transport systems were investigated by incubating tissue for 15, 30, 45, 60, 75, or 90 min. These experiments were analyzed by fitting a mathematical model to the data and calculating values for parameters representing the active and passive components of the transport processes. Pressure did not affect either of the parameters for PAH or for TEA transport. Thus, if helium elicits its known neural effects through an action on cell membranes, that action is not large enough to be detected by this assay system.

Aminohippuric Acids↗
PubMed1982

Sex roles and type A behavior.

Examined relationships between sex-role identification and Type A behavior. Based on Bem Sex-Role Inventory (BSRI) scores, Ss (N = 64) were categorized as Androgynous, Masculine, Feminine, or Undifferentiated; the extent of Type A behavior was assessed via the Behavior Activity Profile. After biological sex had been covaried out, it was found that the Masculine group had significantly higher Type A scores than any of the other three groups. Also, Type A behavior correlated significantly with both the Masculinity and Femininity scales of the BSRI even though the scales themselves were statistically independent. It is suggested that identification with masculine but not feminine traits, while perhaps conducive to psychological health, may be dysfunctional in terms of long-term medical consequences.

Adult↗
PubMed1982

Alkalinization of the incubation medium by rat and rabbit renal cortical slices.

The pH of bathing media containing acetate increased substantially during a 90-min incubation of renal cortex slices from rats and rabbits and did not achieve a steady state after 5 h. Alkalinization of the medium was markedly depressed by cold (0 degree C) and nearly abolished by incubation under 100% N2. Ammonia synthesis did not appear to be an important additional source of base. Incubation of tissue from either species in acetate-free medium reduced but did not abolish base production. Acetazolamide further reduced base production by rat kidney. It was concluded that a portion of the base added to the medium by rat renal tissue reflects the operation of a transport process that separates hydrogen and hydroxyl ions and may be the same one that normally secretes hydrogen ion into tubular fluid.

Acetates↗
PubMed1980

The relationship of sex role to self-concept.

Investigated the relationship of sex role in 136 Ss as measured by the Bem Sex Role Inventory to measures of self-concept and overt anxiety. Persons who rated themselves low in both masculine and feminine attributes were found to have significantly poorer self-concept than both androgynous and masculine Ss, which suggests that this group should be distinguished from high-high scorers labeled as androgynous. There was no significant difference in self-concept between masculine and androgynous Ss, and the masculine group reported significantly lower levels of anxiety. These findings support a previous contention that it is the presence of masculine attributes rather than a balance of masculinity and femininity that is crucial to personal adjustment.

Adult↗