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A Sobotka

Publications and source records attributed to A Sobotka.

9 recordsLinked to original sources
PubMed2004

Imaging findings in three cases of the nodular type of muscular sarcoidosis.

OBJECTIVE: Sarcoidosis is a granulomatous multisystem disorder that may uncommonly involve muscle. We report the sonographic and MRI findings in three cases of the nodular type of muscular sarcoidosis. CONCLUSION: Intramuscular hypoechoic well-defined nodules in young patients or patients with a history of sarcoidosis suggest the diagnosis of intramuscular sarcoid. MRI is useful in detecting muscle sarcoid, evaluating the extent and distribution of muscle involvement, and monitoring the patient during follow-up after steroid therapy. MRI showed nodules that were iso- or hyperintense relative to muscle on T1-weighted sequences. On T2-weighted images and STIR sequences, we observed numerous intramuscular nodules of homogeneous high signal intensity. All nodules enhanced homogeneously on contrast-enhanced T1-weighted sequences. Disappearance of all nodules was seen on follow-up sonograms and MR images after patients had received steroid therapy.

Adult↗
PubMed2002

The patency of the utero-oviductal tract during the estrous cycle in the pig.

The study of corrosion casts after filling the utero-oviductal lumen with heat-hardened resin Mercox, and scanning electron microscopy (SEM) observations of the tissue cross-sections were carried out in 63 pigs during the estrous cycle. Investigations of the corrosion casts showed that the barrier for the transportation through the utero-oviductal canal may occur in the oviductal isthmus, because this pathway was closed for Mercox resin between days 6-21 of the estrous cycle. SEM observations of the oviductal tissues confirmed that the smallest cross-sections of the porcine oviduct were found in the isthmus on 1-1.5 cm from the uterine horn, although with open lumen throughout the estrous cycle. However, in the intermediate parauterine part of the isthmus, with thick muscular layer (2850-3800 microns in a diameter) and with short strongly tighten apical mucous folds, main pathways for the transportation can be parabasal fissures, particularly on days 6-21 of the estrous cycle.

Animals↗
PubMed1999

Oviductal lymphatics and their relations with the paraovarian lymphatic plexus in the pig.

The lymphatic vessels emanating from the oviductal infundibulum, ampulla and isthmus were examined in the pig paraovarian sac and broad ligament walls to determine their relations with paraovarian lymphatic plexus. To differentiate the oviductal, ovarian and uterine lymphatic pathways injections of the three-coloured microfil were used. The precollector lymphatics in the paraovarian sac mesosalpinx created two networks running independently pathways towards the lymph nodes. A large multimesh network from the oviductal isthmus, especially in the late follicular and early luteal phases, together with uterine precollectors made the lymphatic plexus in subovarian areas. Both of these lymphatic networks did not possess direct connections for the lymph flow. The lymphatic system in the supraovarian sac was not evident scanty.

Animals↗
PubMed1999

[Percutaneous radiofrequency ablation of hepatic metastases. Preliminary experience].

AIM: To evaluate the efficiency of percutaneous radiofrequency ablation in the treatment of liver metastases. METHODS: Eighteen patients with 31 liver metastases, mainly from colorectal cancer, 10 - 35 mm in diameter (m = 23), underwent 26 courses of percutaneous radiofrequency ablation. Fifteen patients had previously undergone hepatectomy, and 3 patients had contra-indications to surgery. Imaging guidance was ultrasound in 21 patients, CT in 4 (tumors not seen with ultrasound), and both in 1. A generator working at 450 KHz with a maximum output power of 150 W was used to treat each lesion for 18 - 20 min. Treatment was monitored with real time ultrasound. RESULTS: Among the 12 patients followed more than 3 months, only one of the 24 treated lesions recurred after a mean follow up of 259 ¿ 109 days. Liver disease was controlled in 8 of the 12 patients after 90 - 509 days (m = 306). Among these 8 patients, 3 were tumor free after 559, 378 and 90 days, respectively; 2 died tumor free of non-tumoral disease (pulmonary embolism, digestive bleeding); 3 developed lung metastases treated with chemotherapy (n = 2) or surgery (n = 1). Three of the 12 patients had widespread hepatic tumor occurrence, and one patient died of these metastases. Six patients experienced mild skin burns, but no major complication was observed. CONCLUSION: Radiofrequency ablation of hepatic metastases appears safe and promising in this preliminary experience. Further investigation is needed.

Adult↗
PubMed1999

Morphological features of lymphatic and mesothelial communications in the broad ligament of the pig.

The broad ligament containing uterine, paraovarian, and oviduct lymphatics was examined in the pig in various phases of the estrous cycle using light, scanning and transmission electron microscopy. The architecture of these regions differed and was independent of the lymphangions of the precollector and collector lymphatic vessels. Lymphangions were separated from mesothelium by connective tissue and/or muscle layers; however, in the vicinity of the thin walled paraovarian sac, large lymphangions were often compressed between two epithelial layers. Numerous lymphatic lacunae were in direct contact with the peritoneal and paraovarian sac cavities. The mesothelial lining of the broad ligament and the external and internal epithelium of the pig paraovarian sac displayed two distinct cell types. Only smaller cuboidal cells with prominent microvilli extended above the lymphatic endothelium. The surfaces of these cells were discontinuous and showed: 1) lymphatic stomata, 2) small pores or fenestrae, 3) a superficial network of epithelial-free communications with underlying connective tissue to the paraovarian sac in the postovulatory period independent of the lymphatic vasculature, and 4) endothelial (instead of epithelial) cells with crevice-like discontinuities in large portions of the internal sac surface during the follicular phase of estrus. Numerous lymphatic stomata had orifices composed of flattened cuboidal cells while lymphatic endothelial cells were characterized by macula or zonula adherent connections formed within rims of various sizes (up to 50 microns in diameter). During estrus, there were circular (0.5-2.0 microns) and irregular (to 10 microns) interendothelial openings in stomatal orifices with migrating cells. These morphologic findings suggest that absorption and passage of fluid, particles and cells between cavities and the lymphatic lumen in areas of the paraovarian lymphatic plexus in the pig is feasible.

Animals↗