PubMed Health⌕ Search

Biomedical subjects

A Soi

Publications and source records attributed to A Soi.

3 recordsLinked to original sources

Abdominal incision endometriomas.

General surgeons frequently are asked to evaluate masses appearing in abdominal incisions. The differential diagnosis of these masses is extensive, including suture granulomas, hernias, abscesses, and malignant tumors. When evaluating masses in or near cesarean section scars, endometrioma should also be considered in the differential diagnosis. The presence of endometriomas in and around cesarean section scars clearly has been established in the obstetrics/gynecology literature, with the reported incidence ranging from 0.03 to 0.4 per cent. However, the presence of only two case reports in the general surgery literature suggests underappreciation of this pathologic entity by general surgeons. It also indicates that endometrioma commonly may not be considered in the differential diagnosis of masses detected in or near cesarean scars. Cesarean scar endometriomas are diagnosed by clinical history, with surgical excision as the primary mode of therapy.

Abdomen↗

Acidic and basic fibroblast growth factors are present in glioblastoma multiforme.

Immunohistochemistry was performed on paraffin sections from human glioblastoma multiforme and normal brain tissue. Acidic fibroblast growth factor (FGF) was abundantly present in astrocytes from all glioblastomas studied. Basic FGF was found in the matrix surrounding proliferating blood vessels in most of the glioblastomas. In contrast, astrocytes from normal brain did not contain acidic FGF, and perivascular matrix staining was not demonstrated for basic FGF in the normal brain. Both growth factors could be demonstrated in neurons, Purkinje cells, capillary endothelium, and arterial walls in the normal brain. This study implicates both growth factors in the pathogenesis of malignant glioma. Both may be significant mediators of angiogenesis in glioblastoma.

Fibroblast Growth Factor 1↗