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Biomedical subjects

A Solini

Publications and source records attributed to A Solini.

At least 55 records · Page 3Linked to original sources
PubMed1989

Metal cementless prosthesis for vertebral body replacement of metastatic malignant disease of the cervical spine.

Sixteen patients affected with metastatic malignant disease of the cervical spine underwent cervical vertebral body replacement with an original metal cementless prosthesis. In all cases there was immediate spine stability postoperatively and pain relief. All patients were able to walk within a few days postoperatively without any rigid external support. Follow-up roentgenograms have shown nonprosthetic mobilization.

Adult↗
PubMed1989

Vertebral artery release in vertebro-basilar insufficiency due to cervical uncoarthrosis.

The authors report 31 cases submitted to transversectomy and uncosectomy according to the Jung and Kehr method for the treatment of vertebrobasilar insufficiency secondary to compression of the vertebral artery due to cervical uncoarthrosis. The results obtained were all classified as excellent or good. Emphasis is placed on several diagnostic aspects such as arteriographic investigation, and some details of the surgical technique used for the prevention of complications are discussed.

Adult↗
PubMed1988

Arthrography in the study of extrameniscal pathology of the knee.

We re-examined 800 arthrographies performed between 1984 and 1986 according to the Lindblom-Ficat-Philippe method. 280 had pure meniscal lesions. In the remaining 520 cases, arthrography revealed extrameniscal pathology, sometimes associated with meniscal lesions, as well as other pathologies which were either negative or equivocal. The purpose of this study was to emphasize the advantages of a simple method of diagnosis applicable to out patients in the study of extrameniscal pathologies which are often concealed by the associated meniscopathy. In fact, it is possible to observe chondral, synovial, capsular and ligamentous pathologies which may be very useful as a prelude to diagnostic arthroscopy, which we consider to be a second level test.

Arthrography↗
PubMed1988

Percutaneous lumbar nuclectomy according to the Onik method: indications, technique, first results.

The authors report their first experience with 20 cases of lumbar herniated disc treated by percutaneous nuclectomy according to the Onik method. The methods used for a precise preliminary assessment of the prolapse in order to establish correct indications are discussed. The technique of the operation is then described. The simplicity and relative absence of trauma in this type of surgery, associated with the patient's rapid recovery, drastically reduces hospitalization time, with consequent social and economic advantages. The clinical results at follow-up are sufficiently rewarding to suggest a wider use of this method, but it is essential to restrict it to the indications laid down, which are fully illustrated. The method is applicable only to contained hernias and is contra-indicated in extruded hernias.

Adult↗
PubMed1987

Contrast arthrography in symptomatic varus knees.

The authors carried out a study of contrast arthrography in 48 cases of primary genu varum, i.e. not secondary to trauma or to pathological conditions of the hip or foot. The patients all had symptoms and were classified according to the commonly used Trillat-Dejour method into four groups or stages depending on the degree of varus and the radiographic and arthrographic findings. Associated lesions secondary to the basic pathology were observed in all cases. These ranged from hypertrophic synovitis to torn medial or lateral menisci up to total compromise of the joint typical of stage 4 arthritic varus knee. In these patients, contrast arthrography is useful in planning surgery, particularly high tibial osteotomy. It also enables the surgeon to decide whether complementary intra-articular measures are indicated without having to resort to arthroscopy. This is always a more invasive method, necessitating general anaesthesia, as these knees are quite painful and the arthroscopic access is difficult.

Aged↗
PubMed1986

Somatostatin response to a mixed meal in normals and in type I diabetics.

Somatostatin has been proposed as a regulatory peptide of nutrient entry and fuel homeostasis because of its ability to inhibit the release of substances involved in food digestion and metabolism. The aim of the study was to evaluate the somatostatin response to a test meal in type I diabetics at the clinical onset of the disease and after two months of intensive insulin therapy. Normal subjects and diabetics in good metabolic control showed a characteristic biphasic somatostatin rise after a test meal; this response was lacking in diabetics at the onset of the disease. The response of somatostatin to a mixed meal in normals confirms its involvement in nutrient digestion and metabolism. The lacking somatostatin response in newly diagnosed type I diabetics might be related to deficient GIP response to the test meal or to other factors such as the insulinopenia or metabolic derangement characteristic of the clinical onset of the disease.

Adult↗
PubMed1986

Somatostatin plasma levels and biological effects following subcutaneous administration of somatostatin in man.

The rate at which somatostatin appears in the circulation after subcutaneous bolus injection and continuous administration by pump was determined in normal subjects by serial radioimmunoassays of immunoreactive somatostatin. Following a single subcutaneous injection of 250 micrograms, the somatostatin peak in plasma appeared after 5 min and had only a transient effect on insulin levels. During continuous administration, somatostatin reached levels able to reduce significantly insulin and glucagon. Somatostatin plasma levels exerting biological effects were observed during the subcutaneous administration of the peptide.

Adult↗
PubMed1986

The surgical treatment of cervical metastases.

The basic problem in dealing with metastatic deposits in the cervical spine is to treat the lesion in time, that is, prior to the onset of radicular or medullary involvement. This is always progressive and seriously affects the quality of remaining life in these patients. Early surgical intervention, in fact, makes it possible to free these patients from the prolonged use of orthoses which are often badly tolerated, facilitates easy nursing and often avoids or significantly reduces the pain due to these secondary lesions, so restoring a quality of residual life which is acceptable even in the context of neoplastic disease. After reviewing the world literature and the proposals of various authors, we present our own experience in 28 surgically treated cases. The advantages and disadvantages of the various techniques are discussed. Finally, a flexible metallic cervical prosthesis designed by the authors is presented. This is a shock-absorbent device which is fixed without cement.

Adult↗
PubMed1985

The surgical treatment of metastatic tumours of the lumbar spine.

Thirty-three patients affected by metastases in the lumbar spine were treated surgically with the objective of stabilising the affected area while at the same time alleviating involvement of the neurological structures. The surgical technique was adapted to the type and site of the lesion. The lumbar spine differs from the dorsal and cervical spine in that there are two quite different levels of neurological risk above and below L2. Above L2 it is severe, of rapid onset, and usually irreversible. Below L2 it is more easily reversible, even if surgical intervention is not carried out immediately. In cases with neurological involvement, the results were always very much better in the cases operated on early. This led us to carry out the operation prophylactically with rewarding results because none of these patients subsequently developed neurological damage.

Adult↗
PubMed1975

Pathological fractures due to metastases.

The authors review the literature and report on the treatment of metastatic pathological fractures, on the basis of their own experience of 51 operations. They review the radiological and pathological aspects of the lesions, and the methods of investigation. They stress the need for close collaboration between oncologists, radiologists and orthopedic surgeons, and emphasize the role of surgical treatment in the restoration of function and the relief of pain, by stable synthesis of the affected part. The methods employed are those used in traumatology, together with arthroprosthetic replacement. The importance of ensuring a stable synthesis, for the patients' limited life expectancy, justifies the use of acrylic cement, which often establishes continuity that otherwise would not be attainable. The indications for operation are not related to prolonging life but only to improvement in the quality of remaining life as measured by absence of pain and recovery of function. The results should be assessed primarily from the patient's point of view, the aim being to restore his mode of living before the fracture occurred. This has psychological as well as functional value.

Acrylates↗