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Biomedical subjects

A Sonin

Publications and source records attributed to A Sonin.

7 recordsLinked to original sources
PubMed2001

A closed-cycle capillary polymerase chain reaction machine.

A novel thermocycling machine based on a microcapillary equipped with bidirectional pressure-driven flow and in situ optical position sensors is described. A 1-microL droplet of reaction mixture moves between three heat zones in a 1-mm-i.d., oil-filled capillary using a multielement scattered light detector and active feedback. Dwell times and accelerations can be adjusted independently. As a demonstration of the device, 30 cycles of a 500-base pair product were performed in 23 min with 78% amplification efficiency. This result compares well with previous high-speed thermocyclers. Theoretically, the arrangement can approach a time of 2.5 min for 30 cycle amplifications of a 500-base pair product.

DNA↗
PubMed2000

Fractures of the elbow and forearm.

Fractures and dislocations of the elbow usually occur secondary to indirect trauma. In the adult, fractures of the distal humerus almost always involve the condyles. Fractures of the radial head and neck may be subtle, and the appearance of secondary signs, such as the elevated fat pads from an elbow joint effusion, may be diagnostically useful. Dislocations of the elbow can be associated with fractures, such as those involving the ulnar coronoid process. In children, the presence of epiphyseal and apophyseal ossification centers can confuse the inexperienced observer in the setting of elbow trauma. Osteochondral injury may be difficult to identify without adjunctive imaging techniques, such as magnetic resonance (MR) imaging. Soft tissue injury at the elbow is also well characterized by MR imaging. Fractures of a single forearm bone may occur in isolation, usually due to a direct blow, but these are usually associated with fracture of displacement of the other bone in that forearm.

Adult↗
PubMed1999

Right hemisphere dysfunction: therapeutic intervention from acute care to home health.

This article discusses clinical practice variances in speech-language treatment of patients with right hemisphere dysfunction by therapeutic milieu. With an eye toward enhanced cost effectiveness, a model of intervention is presented that takes a patient from acute care management through rehabilitation. Issues discussed include assessment, family training, goal setting, and documentation. A right hemisphere screening tool is included in an appendix for use in acute and transitional care settings where in-depth testing might be inappropriate because of time constraints or the acute or transitory nature of the patient's symptoms.

Acute Disease↗
PubMed1999

Evanston Northwestern Healthcare--right hemisphere screen.

This article consists of a screening test that has been developed and used by the speech-language pathologists at Evanston Northwestern Healthcare. It is an informal tool designed to quickly determine the cognitive and communication status of right hemisphere-injured patients and is most appropriate for use in acute care and transitional care settings, where speech-language pathologists are asked to determine whether or not a full evaluation is warranted.

Brain Diseases↗
PubMed1991

Juxta-articular calcifications in secondary hyperparathyroidism: resorption after parathyroidectomy.

Soft-tissue calcification in chronic renal failure has been described, but little is understood about its pathogenesis or progression. Our patient's case is a dramatic example of complete resorption of soft-tissue juxta-articular calcification in secondary hyperparathyroidism after removal of parathyroid gland tissue. This resolution is most likely due to normalization of the calcium-phosphate ion product.

Adolescent↗