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Biomedical subjects

A Sortini

Publications and source records attributed to A Sortini.

At least 37 records · Page 2Linked to original sources

[Chemo-antibiotic prophylaxis in general surgery. A study of 1722 cases].

Up until now the problem of surgical infections has been one of the most important which surgeons must confront daily. In 1989 our Institute began programs for control and surveillance of surgical infections; these include, among others, the use of chemo-antibiotic prophylaxis protocols applied to all of the patients hospitalized for surgery. The authors report two years application of three protocols of chemo-antibiotic prophylaxis related to 1722 patients, in which we pointed out the passage from 27.6% of infected cases in the control group to 10.2% infected cases in one of the groups subject to prophylaxis. In these cases the antibiotic prophylaxis also acted reducing in a spectacular manner the incidence of clinically not significant infections.

Anti-Bacterial Agents↗

[The implantation of a heterologous prosthesis in reparative abdominal-thoracic surgery. Experience with the use of clindamycin in preventing prosthesis-related infection].

The authors point out how infection of heterologous prosthesis, widely used in surgery, can be a dramatic event. On the other hand, antibiotic prophylaxis is difficult because of the difference between "in vitro" and "in vivo" activity of many antibiotics, due to the production, by many bacteria, of the so-called glycocalyx. This would allow bacteria to clump and adhere to many surfaces, forming micro-colonies, causing delay in phagocytosis, and reducing the efficacy of antibiotics. On the basis of their, although limited, experience, the authors suggest, for the prophylaxis of prosthesis infection, the use of antibiotics such as clindamycin, able to reduce glycocalyx production.

Abdominal Muscles↗

[Comparative scintigraphic functional study of 3 different reconstruction technics following total gastrectomy].

Esophago-jejunal reconstruction, after total gastrectomy, is best performed by one of the following three operations: interposed jejunal loop, Roux-en-Y loop and "omega" loop with Braun anastomosis. To assess the effects of the three mentioned techniques three groups of 15 patients each were examined after total gastrectomy for I, II or III stage cancer. Four to ten months after surgery all patients underwent the following tests: a) esophago-jejunal transit with labeled solid meal; b) cholangio-scintigraphy and c) absorption test of biliary acids. A group of 10 patients, without gastrointestinal pathology, was selected for comparison. The data obtained from the comparative study, in agreement with the opinions held by many Authors and our previous research, demonstrate that the interposition of jejunal loop (Mouchet) is the reconstructive technique closest to the unoperated stomach and, for this reason, is to be preferred after total gastrectomy.

Bile Acids and Salts↗

[Use of imipenem-cilastatin in antibiotic therapy and prevention in general surgery. One year of clinical experience].

The authors report one year of clinical experience with imipenem-cilastatin, first antibiotic of thienamycin class, in the therapy and prophylaxis of postoperative infectious diseases. One hundred thirty four patients were treated with antibiotic therapy and 10 days after in 98.5% of cases a clinical remission of the disease was obtained; only in 2 patients the effect wasn't evaluable because they died for not drug-related causes. The prophylactic use of this antibiotic was limited to 34 patients with high risk of infectious diseases; only 3 cases (8.8%) showed bacterial contamination and one of them had clinical signs of disease which indicated the absolute need for antibiotic therapy. The Authors also emphasize the excellent results, the tolerability of the drug and the absence of side-effects.

Adult↗

[Effects of therapy with aminaftone on chronic venous and lymphatic stasis].

Following a short introduction on the physiopathology of the phlebo-lymphatic system, the results of a study carried out on 114 patients suffering from chronic venous insufficiency (CVI) treated at the Department of General Clinical Surgery and Surgical Therapy of the University of Ferrara are reported. These patients were subdivided into two random groups and treated with common phlebotonic drugs and aminaftone, respectively. Both groups were also subjected to those physical and medical measures that are usually adopted for the treatment of such patients. The therapeutic effects were assessed by comparing symptomatology before and after 90 days of treatment, both subjectively (patient's assessment of the symptoms by means of a scoring system) and with objective methods (measurements and echo-Doppler examinations). The differences between the two groups were statistically very significant in favour of patients who had taken aminaftone. Excellent results were obtained in the treatment of CVI as well as in lymphatic-related pathology (lymphedema).

4-Aminobenzoic Acid↗

[Technical notes on the use of the circular mechanical stapler].

The Authors, in the light of their experience, study some technical aspects in the use of circular stapling devices (SPTU-EEA). After paying attention to the risks involved in the employment of such instruments, they explain the precautions they consider necessary to prevent the most common complications. As a conclusion, they confirm the safety of stapling devices, provided they are used with skilfulness and caution.

Esophagus↗

[Aneurysm of the abdominal aorta (our experience)].

The AA. report their experience on 22 cases of aneurysm involving under renal abdominal aorta as mortality rate in elective surgery is about 16% and in emergency operation it rises up to 60%. The AA. remark the opportunity of early surgical treatment. Ti decrease mortality rate.

Aged↗