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Biomedical subjects

A Sotto

Publications and source records attributed to A Sotto.

At least 73 records · Page 4Linked to original sources
PubMed1988

[Long-term study of patients with active chronic hepatitis treated with leukocyte interferon].

Seven patients with active chronic hepatitis who received Interferon Alfa showed a marked humoral and histological improvement one year after the treatment was concluded, in 3 patients the hepatic histology was almost normal, 2 evolved to a persistent chronic hepatitis and only one showed deterioration. These results differed from those obtained immediately after the treatment (p 0.05). Interferon Alfa proves to be of the most usefulness in this disease, studies should be continued up to one year after the treatment has ended.

Follow-Up Studies↗
PubMed1985

[Hepatic manifestations in giardiasis].

In 25 patients with diagnostic of Giardiasis by duodenal intubation we studied the hepatic functional tests and hepatic biopsy. 60% of patients presented alterations of hepatic histology; 36% steatosis and 24% inflammatory lesions, chronic persistent hepatitis 3 cases and chronic active hepatitis two of them. Hepatic lesions regression was reached only with antiparasitic treatment and in some cases reappearance of lesions depended on parasitic's reinfections. For every patient with histologic diagnosis of chronic hepatitis without viral markers we suggested to dismiss Giardiasis and to treat it before to undergo other therapeutical behavior.

Adult↗
PubMed1985

[T and B lymphocytes in hepatic diseases].

T and B. lymphocytes in peripheral blood were determined in 102 patients with several hepatic diseases: acute hepatitis, persistent and chronic active hepatitis and hepatic cirrhosis. Significant differences (p less than 0.05) were found between all groups of patients and controls. T lymphocytes were decreased (p less than 0.05) in patients with acute hepatitis that developed chronic disease in relation with those with good evolution. A remarkable decrease was found in cirrhotic patients with hepatic insufficiency. The prognostic value of these lymphocytes populations in hepatic diseases is enhanced.

Adult↗
PubMedDate not supplied

Bifocal cervical spondylodiscitis due to Citrobacter diversus.

Spondylodiscitis due to Citrobacter diversus is rare. An unusual case of bifocal cervical spondylodiscitis following transurethral prostatectomy is reported. C. diversus was detected by urinary cultures and locally by intervertebral disc puncture. Satisfactory recovery occurred after treatment with imipenem and amikacin, and then imipenem alone. Citrobacter infections are still rare in adults but are increasing in immunocompromised patients and sometimes occur in healthy subjects following surgery.

Aged↗
PubMedDate not supplied

[Diagnosis of acute abdomen by means of laparoscopy (experience in 6,400 cases)].

A study of 6,400 cases of Emergency Laparascopy (E.L.) was made in the Instituto de Gastroenterología de Habana, Cuba. The objective of the E.L. is to provide a diagnosis when other methods have been unable to do so. The most frequent diseases found were: gynecological problems, acute appendicities, and acute cholecystopathies. The E.L. is of great usefulness as in many cases an exact diagnosis is possible thus avoiding unnecessary surgery. The reliability of the method is good, permitting an exact diagnosis in 98% of the cases. In all the authors' cases the diagnosis was confirmed by either surgery or the evolution of the disease. The authors recommend the creation of emergency laparascopy services in which all the resources would be centralized: sufficient medical staff to ensure 24-hour service, specialized technicians, and the necessary material. They add that even though in their country it is of little importance, their experience leads to the conclusion that this type of organization is medically profitable.

Abdomen, Acute↗
PubMedDate not supplied

[Study of lymphocyte subpopulations by means of monoclonal antibodies in acute hepatitis A and B].

We studied T3, T4 and T8 lymphocyte populations in peripheral blood by monoclonal antibodies in 40 patients with acute viral hepatitis (Type A 20; Type B 20) who underwent outcome to complete recovery. We compared the results with 20 healthy subjects (control group). We found a decrease in total lymphocytes measured by T3 monoclonal antibodies and a significant increase in T8 lymphocyte populations compared with control groups. In the early stage the T4/T8 ratio was decreased. Lymphocyte populations and T4/T8 ratio was normal in 3-6 month follow-up for the acute A hepatitis group and 3.6 month to a year follow-up for the B hepatitis group. Results were related to the humoral and clinical outcome.

Adolescent↗
PubMedDate not supplied

[Drug interactions and antibiotics].

Situations that require the use of systemic antibiotic therapy are common and drug interactions are potentially frequent. These interactions may be deleterious and lead to reduction of therapeutic index, enhancement of toxic risk or may be favourable, with optimization of pharmacokinetics or pharmacodynamics. The mechanisms of these interactions are discussed.

Anti-Bacterial Agents↗