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Biomedical subjects

A Stańczyk

Publications and source records attributed to A Stańczyk.

11 recordsLinked to original sources

[Frequency of antibodies against Trichinella spiralis and Echinococcus ssp. appearance in children with atopic diseases].

Parasitic infestation and atopic diseases have common features. The aim of our study was to evaluate the occurrence of Trichinella and Echinococcus seropositivity in children with atopic diseases. The study group involved 72 children aged from 2,5 to 18 years with asthma and allergic rhinitis. The control group comprised 30 children without allergic diseases. In 12 children with atopic diseases the serological tests were positive for Trichinella spiralis, in II for Echinococcus spp. and in 5 both for Trichinella and Echinococcus. In control group the serological tests were positive in 3, 6 and 3 children respectively. There were no differences in occurrence of positive results of serological tests in children with atopy and children without allergic diseases.

Adolescent↗

[AIDS syndrome in an eight-month-old infant].

The paper presents multiorgan manifestations of AIDS syndrome in an infant at the age of 8 months. The child was admitted to the Clinic with enteric disorder, anaemia, hepatosplenomegaly and pneumonia. The diagnosis of those anomalies and the treatment of pneumonia took much time. Infection with CMV was recognized but, despite the treatment and elimination of the virus, the child's condition did not improve and general emaciation progressed. The diagnosis of AIDS syndrome was based upon indicator illnesses: chronic recurrent pneumonia, cytomegaly and emaciation syndrome as well as upon the results of additional examinations, first of all including the presence of p24 antigen in the serum. In children with chronic diseases and manifesting non-specific multiorgan symptoms we should take into consideration AIDS syndrome in the differential diagnosis.

Acquired Immunodeficiency Syndrome↗

Arylamine N-acetyltransferase (NAT2) gene mutations in children with allergic diseases.

The overrepresentation of phenotypically slow acetylators among patients with atopic allergy has been reported in previous studies. The N-acetyltransferase coding gene has not yet been investigated in allergic diseases. This study was designed to determine the differences in the distribution of mutation frequency and genotypes that encode normal and defective activity of N-acetyltransferase in children with atopic allergies compared with healthy children. In 56 children with documented inhalational, food, or mixed allergies and in 100 healthy control children with no clinical or laboratory signs of allergy, the genotype coding for N-acetyltransferase was identified by means of the polymerase chain reaction followed by analysis of restriction fragment length polymorphism. Nucleotide transitions in the following positions were investigated: 481 C-->T, 590 G-->A, 803 A-->G, and 857 G-->A, which enabled the identification of six genotypes, including the wild-type (wt) allele, and 16 genotypes, including mutated alleles (homozygotic and herterozygotic). The statistical analysis showed significant differences in the distribution of the frequency of the occurrence of mutated alleles and genotypes between the two groups of children. In 51 children (91%) with allergy, genotypes that encode acetylation defect were found; genotypes that code for normal N-acetyltransferase were observed in only five allergic children (9%). In the control group the distribution of genotypes coding for normal and defective N-acetyltransferase activity is 38% and 62%, respectively. Thus study enabled the conclusion that the slow acetylation genotype is a genetic marker of predisposition to atopy.

Adolescent↗

[The evaluation of respiratory function in children with chronic allergic rhinitis].

The aim of the paper is to assess respiratory functions in children with chronic allergic rhinitis. Multiple spirometric measurements were performed during oral and nasal ventilation and after nasal provocation with histamin and allergen. We find that spirometric measurements during nasal ventilation are very useful because they objectivize the degree of nasal patency disturbances. We have also noted the occurrence of bronchospastic reactions after nasal provocations.

Adolescent↗

[Evaluation of the respiratory system function in girls from the Textile Technical College in Lódź (II)].

The work in textile industry is a risk factor of the development of chronic non-specific diseases of the respiratory tract. Thus the vocational selection for the posts in this industry should particularly take into account the health status of the applying youths. The subjects of the study were 35 girls from Textile Technical College and 42 girls from Grammar School (control group). The girls were examined three times in the succeeding school years. Anthropometric and spirometric examinations were performed. No significant differences between the values of ventilation parameters in both the groups were observed, which indicates that the selection of pupils admitted to the Technical College was proper. During the period of professional training no adverse effects of the industrial environment on the respiratory function could be found either.

Adolescent↗

[Evaluation of somatic development, physical fitness and motor skills of girls from the Textile Technical College in Lódź (I)].

Thirty-five girls from a technical college (TC) and forty-five from a grammar school (GS) (a control group) were included in a long-term examination. Somatic traits have been investigated for 4 years, while aerobic capacity and motor efficiency have been studied for 3 years. The preliminary selection was noticed in girls--candidates to technical college and grammar school. These two groups of girls differed in respect of social factors and somatic predisposition. At the beginning of the examination the girls from the technical college revealed a considerably lower motor efficiency as compared to those from the GS. After 3 or 4 years of learning traits of the body length were still weaker in the girls from the technical college. However, they had a more massive skeleton, stronger trunk muscles and stronger hands. In addition, these girls were characterized by a remarkable improvement of general physical efficiency, particularly endurance, speed and nimbleness. In the final stage of the study in all girls from both TC and GS aged 18 lower aerobic capacity in comparison with data from the previous year was found, which could results from inefficient physical activity during the educational process. This fact may be especially unfavourable for the girls from TC as far as their future profession is concerned.

Adolescent↗