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Biomedical subjects

A Stapiński

Publications and source records attributed to A Stapiński.

At least 37 records · Page 2Linked to original sources
PubMedDate not supplied

[Rapid spread of HIV infections among narcotic addicts].

In the Institute of Venereology, 5351 patients (75.1% of males, 24.9% females), intravenous drug users (IVDU), have been tested for the presence of HIV antibodies in the period from Jan 1986 to Dec 31 1989. They were patients of detoxication wards and/or pensioners of drug treatment centers. HIV antibodies were determined by the EIA method (Abbott Recombinant HIV-1 EIA test), and positive results were confirmed by the western-blot technique. HIV antibodies were found in 292 patients: 228 males (78.1%) and 64 females (21.9%), which accounts for 5.5% of tested IVDU. In 1986-1987 all tests were negative, although the first HIV infection was confirmed in 1985 in homosexual group. The first positive HIV test in drug addicts was detected in Aug 1988 after testing of 2254 patients. In 1989 276 sera were positive for HIV antibodies (11.2%) among 2471 patients studied. Our study indicates that HIV infection is spreading rapidly in IVDU population. Infections of drug addicts with HIV represent 66% of total detected cases of HIV antibody-positive individuals in Poland; among 30 diagnosed AIDS cases 5 were drug users.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

[Diagnostic and prognostic significance of various changes in the skin and mucous membranes in HIV infection].

The prognostic and diagnostic importance of certain cutaneous lesions in HIV infection is discussed. In own patients of interest was the frequency of oral candidiasis (30%) and extensive seborrhoeic changes and persistent eruptions of the type of molluscum contagiosum in a patient with the AIDS-dementia complex which were associated with oropharyngeal candidiasis.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

[Results of preliminary clinical studies of patients with HIV antibodies].

In the outpatient clinic of the Institute of Venereology clinical examinations were carried out in 37 patients with HIV infection, who were in a good general condition. In 28 patients peripheral lymphadenopathy was present, with involvement of the lymph nodes in at least two areas besides groins in 15 cases (40.5%). In 11 cases oral candidiasis was present, in one out of 6 females vaginal candidiasis was found. Seven patients (19%) had moderately intense seborrhoea, one (3%) had seborrhoeic dermatitis. Paradontosis was found in 4 patients (11%), 5% had follicular keratinization and 5% had recurrent pharyngitis and high fever. In some cases short-lasting maculoerythematous rash developed on the chest and face or chest and on the legs, recurrent herpes, paraparesis, and a history of short-lasting convulsions developing 6-10 days after alleged infection. In some patients 2 or 3 above mentioned symptoms occurred at the same time.

AIDS Serodiagnosis↗
PubMedDate not supplied

[AIDS--the most important events in 1988. The London Declaration. Resolution on avoiding discrimination].

Two documents are discussed whose acceptance the author considers as the most important events in 1988 in the control of AIDS, that is the London Declaration and the Resolution of the 41st World Health Assembly concerning avoiding of discrimination of subjects infected with HIV and AIDS patients. Both these documents are of essential epoch-making importance for facilitation of the trend of the further prophylactic actions conducted for halting the AIDS epidemic in the whole world.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

[Incidence of HIV infections among the patients of the outpatient clinic of the Institute of Venereology].

The presence of anti-HIV antibodies was sought in 1061 patients (818 men and 243 women) with various sexually transmitted diseases; the group of men contained 29 homosexuals (3.5%) and 26 were bisexual (3.2%). Together these deviants accounted for 7.1% of the group. EIA test confirmed with the Western-blot test gave positive result in 11 patients, including 10 homosexual and bisexual men, that is in 18.2% of the subgroup of men with this deviation, and in 1 heterosexual man (0.13%). Over one-half of them had or had had syphilis, and in the subgroup of homosexuals the patients with syphilis amounted to 36%. The proportion of HIV infections in homosexuals, patients of outpatient clinics for sexually transmitted diseases, is much higher than in heterosexual patients in these clinics and homosexuals not treated in these clinics. Patients in outpatient clinics for sexually transmitted diseases are a high risk group for HIV infection (especially homosexuals with syphilis) and should be tested for the presence of anti-HIV antibodies.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

[Incidence of HIV infection among homosexuals].

In the period 1985-1988 blood samples were examined of 1297 homosexual and bisexual men. The samples were sent by health service units from the whole country. Anti-HIV antibodies were demonstrated by the EIA method and confirmed by the Western blot technique in the serum of 35 subjects (2.7%). In the second half of 1988 a rise was observed in the number of infections among the tested subjects (10.3%). In Poland similarly as in West Europe and the USA, homosexual and bisexual males are the group of high risk for HIV infection.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

[Prevention of HIV infection among drug addicts].

The studied group comprised 2651 patients from detoxication centres and dehabituation treatment institutions who were addicts taking intravenous drugs (71.5% males and 28.5% females). In 12 patients, including one foreign (from Spain) anti-HIV antibodies were found (0.5%). In the years 1986-1987 all tests gave negative results, the first positive result was obtained in 1988, after testing of nearly 1900 patients. In the second half of 1988 positive results were more frequent, since in a group of 400 subjects tested between August and November 10 were positive (2.5%). This shows that the infection spreads rapidly in this population. At the end of November infections among drug addicts accounted for 12.2% of the total number of HIV-positive cases found in Poland. The authors predict a further rapid spreading of this infection in this risk group and postulated gratuitous providing of addicts with dispensable syringes and needles and condoms, and providing systematic intensive training of the personnel of dehabituation treatment institutions as well as extensive informational education of the addicts.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

[The program of prevention and control of AIDS in Poland].

The programme accepted in Poland since November 1988 evolved in accordance with the WHO directives for stopping of infection spread is discussed. The programme includes multidirectional activities: training of staff, diagnostic facilities and research units, prevention of infection by sexual transmission, with blood, needles and syringes. The programme lays stress on the methods for protection of health service workers against infection. Much attention was given to health education for the high risk groups and for the population, especially adolescents. Health education is connected with prompting for the serological testing of anti-HIV antibodies which is principally voluntary. In accordance with the London Declaration and the WHO Resolution on prevention of discrimination of HIV-infected patients and AIDS patients the programme considers these aspects.

Acquired Immunodeficiency Syndrome↗
PubMedDate not supplied

[Usefulness of the gonozyme (Abbott) test in the diagnosis of gonorrhea in prostitutes].

A group of 326 prostitutes were examined for gonorrhoea and the result was positive in 45 cases (14%). Smears were stained with methylene blue and by Gram's method, cultures were conducted on suitable media and the immunoenzymatic method EIA-Gonozyme (Abbott) was used. Smear evaluation was insufficiently sensitive and specific, but it made possible a rapid diagnosis of 17 cases. Most positive result were obtained with the Gonozyme test (41 cases), including 15 women (37%) in whom a positive result was obtained only in urethral secretion, despite a negative result of the examination of cervical secretion. Gonococci were cultured in 29 cases (9%), including 5 (17%) with bacterial growth obtained only from the urethral secretion in 13 (45%) only in cervical secretion. In 27 of these patients the Gonozyme test was positive. Gonozyme was highly useful in the examinations of prostitutes in view of its sensitivity and the fact that the gonococcal antigen can be detected also when the result of culture was negative due to antibiotic taking. Always secretion from the urethra and cervix should be examined, since in 17% of the infected women the diagnosis was established by culture and the Gonozyme test demonstrated infection only in urethral secretion in 37% of the infected women.

Antigens, Bacterial↗
PubMedDate not supplied

[Teaching of dermatology and venereology in Warsaw before the establishment of the first departments of these specialties in Poland].

Teaching and scientific activities were discussed of the outstanding surgeons and internists lecturing on dermatology and venereology at the Academic Faculty of Medicine existing in the years 1809-1816 and at the Faculty of Medicine of The Warsaw University closed by the tsarist authorities after the November Insurrection in 1831. The academic school of medicine could begin its work after a pause of 25 years in 1857 as The Medical-Surgical Academy transformed in 1862 into The Medical Faculty of The Central School closed definitely in 1869 when a Russian university was founded in its place. Those who rendered the greatest services in the development of dermatology and venereology in Warsaw were, among others, Józef Czekierski, Andrzej Janikowski, Antoni Le Brun, and Polikarp Girsztowt, and in the first place Bronisław Chojnowski who raised it to the rank of a clinical discipline. After closing of The Central School the main center for the Polish dermatologists and venereologists was The St. Lazarus Hospital.

Dermatology↗
PubMedDate not supplied

[HIV infection--a sexually transmitted disease].

In the light of literature reports and own experiences and observations the most important epidemiological aspects of HIV infection acquired through sexual contacts are discussed, including the likelihood of infection during heterosexual or homosexual intercourse, factors increasing the infection risk in homosexuals intercourse and the more or less safe forms of sexual intercourse. The combination of HIV infections with infections with other sexually transmitted diseases is discussed on the basis of own observations which showed that HIV infection was acquired much more frequently by homosexuals treated in outpatient clinics for venereological diseases (19.7%) as compared to other homosexual groups (2.7%), and the risk was even lower in heterosexuals treated in these clinics for sexually transmitted diseases (0.2%). Over half the patients infected with HIV had or had had syphilis. HIV infection was sought for in Warsaw prostitutes, and 0.6% of them were found to be infected, two-thirds of the infected ones were drug addicted prostitutes. The importance of the sexual route of infection in drug addicts and transmission of this infection to the heterosexual population are considered. The principles of prophylaxis, the directions of health education, and the importance of screening for HIV infection prevention are considered. Attention is called to the harmful effects of all types of restriction of the infected people which lead to trials of infection concealment.

Acquired Immunodeficiency Syndrome↗