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Biomedical subjects

A Stefanova

Publications and source records attributed to A Stefanova.

5 recordsLinked to original sources

[Transfusion management].

Contemporary transfusion medicine is based on the application of correct indication, volume and regiment of therapy with blood components and plasma preparations according to individual needs and clinical condition of each patient. The goal is to achieve maximally efficient transfusion therapy, rational usage of donor blood, prolonged possibility for blood conservation and decrease of the risk for side effects, complications and infections during the blood transfusion. The new tendency in transfusion therapy is applied in protocols and methodological manuals which give the guidelines, therapeutical algorithms for good medical practice. An example of such manual is the one given by the Council of Europe, which is issued annually and is corrected by wide number of specialists.

Blood Transfusion↗

[Autohemotransfusion].

The new tendency in used transfusion practice in surgery treat the problem of blood loss and its supplementation with minimal transfusion risk. Transmissive infections and immune complication after blood transfusion are still actual today. The autotransfusion is reasonal alternative in modern transfusion therapy.

Blood Component Transfusion↗

[Pregnancy with Rh-isoimmunization. Results of a retrospective analysis in the maternity hospital "Maichin Dom"].

UNLABELLED: The aim of the study is to analyze the outcome of pregnancies complicated by Rh-isoimmunization for the period 1996-2001 and to outline the aspects of optimization of the obstetrical conduct. MATERIAL AND METHODS: The current study includes 39 pregnant women with Rh-isoimmunisation to whom amniocentesis and cordocentesis was performed. All cases were analyzed using medical history, serology (indirect Coombs, PAP test), ultrasound examination, amniocentesis, cordocentesis, NST. RESULTS: From 39 pregnancies, complicated by severe Rh-isoimmunization 36 resulted in a live delivery, 2 resulted in intrauterine death of the fetus and 1 in early neonatal death. The titre of the antibodies is of prognostical value only in the first isoimmunised pregnancy. In this case there is a reliable correlation between the condition of the newborn and the zone from the Liley curve, antenatally found. With history of former immune pregnancies with unfavourable perinatal outcome most precise information about the condition of the foetus gives the cordocentesis. CONCLUSION: In all of the discussed cases the Rh-isoimmunization is a result of no andi-D immunoglobulin profilaxis post partum or following abortion. That is why the efforts should be directed towards conduction of proper profilaxis to all Rh-negative pregnant women.

Blood Transfusion, Intrauterine↗