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Biomedical subjects

A Syrota

Publications and source records attributed to A Syrota.

9 recordsLinked to original sources

[A fast transient osmotic method. Simultaneous in vivo determination of the reflexion coefficient and of the permeability/filtration coefficient ratio of the pulmonary capillary endothelium in the dog].

Thermodynamic variables characterizing the transport of water and urea across Dog pulmonary capillary membrane were obtained in vivo by means of a pulse transient osmotic method. Results were inconsistent with the hypothesis of a homoporous membrane. When data were interpreted in terms of an exclusive water channel and of a shared pore pathway, the value of the pore reflexion coefficient was close to zero for urea.

Animals

[A fast osmotic transition method for the study of pulmonary transcapillary exchange: theoretical model].

A theoretical model allowed the simultaneous determination of the reflexion coefficients of capillary membrane to small hydrophilic molecules and of the ratios of their permeability to filtration coefficient. This was applied to dilution curves obtained after injection of a hypertonic solution containing a vascular tracer. The calculated variables did not depend on the capillary exchange surface area.

Capillaries

[11C]methionine pancreatic scanning with positron emission computed tomography.

By the use of [11C]methionine and positron computed tomography (PCT), images of the pancreas were obtained in 32 patients. The injection of between 10 and 20 mCi of this product enables four to six transverse sections to be obtained. Seventeen of the patients studied had no exocrine pancreatic disease, and in all these cases the pancreas was clearly visible. In four cases of pancreatic carcinoma and one of retroperitoneal tumor, there were abnormalities visible. In five cases of chronic pancreatitis, no pancreatic uptake was observed. In a sixth case, concentration was visible, but only in the head of the pancreas. One case of acute pancreatitis, which showed no concentration during the acute phase, returned to normal after recovery. When visible, the pancreas was easily located and distinguishable from the intestinal image, except in two cases that were uninterpretable for technical reasons. No false positive or negative was observed, but a differential diagnosis between cancer and pancreatitis was impossible.

Carbon Radioisotopes

Infinite dilution conductimetry of plasma and urine: correlation with osmolality.

The infinite dilution conductivity (IDC) of plasma and urine allows a measurement of the electrolyte content in small samples (5 to 15 microliter). The method was compared to the corrected osmolality (II'p) measured by the freezing-point depression. A linear correlation existed between II'p and the IDC: for plasma: II'p = 13.10 sigma o,p + 37.00 (n = 46 and r = 0.9949) for urine: II'u = 12.75 sigma o,u + 16.56 (n = 85 and r = 0.9504). The measurement of the IDC does not depend on protein concentration and can be used instead of the osmometer methods to determine the total plasma and urine electrolyte content.

Blood Physiological Phenomena