Necrotising enterocolitis--an overview.
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Enterocolitis, Pseudomembranous↗
Biomedical subjects
A T Ang
Publications and source records attributed to A T Ang.
Giant epignathus with intracranial teratoma in a newborn infant.
A male newborn infant with a giant epignathus associated with intracranial teratoma and obstructive hydrocephalus detected antenatally is reported. Only 4 similar cases have been reported in the literature. This disorder is uniformly lethal. We believe this is the first reported case of epignathus with congenital intracranial teratoma diagnosed antenatally by ultrasonography.
Adult↗
Reliability of the Dinamap non-invasive monitor in the measurement of blood pressure of ill Asian newborns.
Four hundred thirty-one paired sets of readings of systolic and diastolic blood pressure and 438 paired sets of readings of mean arterial BP from 49 ill newborns, including 21 very low birth weight infants, were analyzed for the extent and pattern of agreement and the linear relationship between the Dinamap oscillometric monitor and the direct intraarterial blood pressure readings. Agreement between the two methods was measured by the intraclass correlation, whereas the linear relationship was assessed by the product-moment correlation. The intraclass correlations for systolic, diastolic and mean blood pressures were 0.696, 0.766, and 0.781, respectively. The product-moment correlations for systolic, diastolic and mean blood pressures were 0.706, 0.768, and 0.786, respectively. BP measurements by the Dinamap monitor showed reasonably close agreement to those obtained by the intraarterial mean arterial pressure ranges above 40 mmHg. For mean arterial pressure of 40 mmHg and lower, BP readings by the Dinamap monitor tended to be higher than those obtained by the intraarterial method. These findings appeared to be consistent regardless of the birth weight of the newborn.
Asian People↗
The usefulness of CRP and I/T ratio in early diagnosis of infections in Asian newborns.
The greatest challenge in neonatal infection is to correctly identify an infected neonate and not to overtreat those who are not. We studied 80 Asian neonates suspected of sepsis. C-Reactive Protein (CRP), Total White Cell Count (TW) and Immature to Total Neutrophil Ratio (I/T ratio) were evaluated in terms of their specificity, sensitivity, positive and negative predictive values. CRP was measured quantitatively by Fluorescence Polarisation Immunoassay Technology (FPIT). There were 36 positive cases (positive blood culture or Chest Radiography [CXR] showed pulmonary infiltrates). Using the FPIT, CRP in 98% of clinically healthy individuals is (less than or equal to) 1.0mg%. When CRP is less than or equal to 1.0mg% is taken as norm, its specificity range from 0.84-0.91 and its sensitivity from 0.22-0.50. However, CRP may be marginally raised in conditions of stress like birth asphyxia and fetal distress. Thus when CRP less than or equal to 1.5mg% is considered as norm, its specificity range from 0.93-1.00 and its sensitivity from 0.14-0.33. The positive predictive value range from 71%-100% and the negative predictive value from 57%-63%. The normal I/T ratio is less than 0.2. The specificity of I/T range from 0.75-0.91 and the sensitivity range from 0.22-0.47. The positive and negative predictive values range from 60%-76% and 58%-66% respectively. Hence CRP is very specific especially when it is less than 1.5mg% but not as sensitive. I/T although less specific is also more specific than sensitive. Combining CRP and I/T as a marker of sepsis only increases its specificity (range 93%-100%) but not its sensitivity (range 16%-45%).(ABSTRACT TRUNCATED AT 250 WORDS)
Asia↗