Biomedical subjects

A T DUDANI

Publications and source records attributed to A T DUDANI.

7 recordsLinked to original sources

PubMed1964

MILK-CLOTTING ENZYMES FROM MICROORGANISMS.

A total of 230 cultures of fungi and 43 cultures of bacteria, isolated from such sources as soil, butter, and milk, were screened for their milk-clotting activity. The fungi were cultivated on semisolid media, and the bacteria were grown in milk media in shake culture. Phytic acid, added as calcium phytate, was found to stimulate production of the enzyme in most of the bacterial isolates. Proteolytic activity was invariably found to be associated with the milk-clotting enzyme in bacterial isolates. There was considerable variation in the ratio of the two enzymes from strain to strain.

Animals↗

PubMed1961

Blood-level duration limit test of procaine benzylpenicillin in sheep.

Rabbits have commonly been used for testing the blood-level duration limit of penicillin, but have proved not to be entirely suitable. Experiments reported in this paper on the use of sheep suggest that these animals can be successfully used for the testing of procaine benzylpenicillin with aluminium monostearate (PAM).Penicillin levels were examined in the blood of 79 sheep 72 hours after intramuscular injection of 75 000 International Units of penicillin; 73 of the sheep sera showed a penicillin level corresponding to not less than 0.03 IU of penicillin per ml. The results are also reported of the comparative testing of four batches of penicillin for blood-level duration limits in both human subjects and sheep.

Animals↗

PubMed1957