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Biomedical subjects

A T Pratt

Publications and source records attributed to A T Pratt.

2 recordsLinked to original sources

Multiagent chemotherapy for sarcoma diagnosed during pregnancy.

A 21-year-old, gravida 1, para O, woman presented at approximately 25 weeks gestation with a large Ewing's sarcoma involving her iliac wing. She was treated with multiagent chemotherapy before a successful Cesarean delivery of a normal infant at approximately 34 weeks gestation. Four years later both the mother and child are doing well. The literature regarding sarcoma occurring during pregnancy and that regarding multiagent chemotherapy in pregnant patients is reviewed. Chemotherapy should be instituted early in the course of many malignant sarcomas, despite pregnancy, to prevent the occurrence of metastases.

Adult↗

Cecal volvulus in pregnancy.

Cecal volvulus in pregnancy is an uncommon complication. A case is reported of a 28-year-old white female, gravida 2, para 1, who presented at 36 weeks' gestation with flu-like symptoms accompanied by regular uterine contractions every 3 minutes; she underwent repeat cesarean section without incident. The patient did well until the second postoperative day, when she developed obstructive bowel symptoms and underwent emergency laparotomy. Operative findings revealed cecal volvulus with partial malrotation of the small bowel, absence of the ligament of Treitz, agenesis of the left kidney, and a redundant sigmoid colon. Medical and surgical management of this case, as well as a general description of the symptoms of cecal volvulus, is discussed. Early diagnosis and operation are essential to avoid the high morbidity and mortality associated with this disease.

Adult↗