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Biomedical subjects

A Taha

Publications and source records attributed to A Taha.

41 records · Page 3Linked to original sources
PubMed1975

Masked diabetic mastoiditis.

Seven cases of elderly diabetics suffering from ths so-called 'malignant external otitis' are presented. Chandler (1968) and others consider that this disease is localized to the external ear canal. We do not agree and believe that it is due to a masked middle-ear infection extending through the tympano-mastoid cells to the mastoid process, sparing the antrum and bulging into the floor of the external meatus. In time, extension to petrous apex results in petrositis and a fatal end in many cases.

Adult↗
PubMedDate not supplied

Preproinsulin messenger ribonucleic acid in the rat adrenal gland.

Many studies support the concept of insulin synthesis in tissues other than the pancreas. Our previous investigations have demonstrated the presence of insulin immunoreactivity in the adrenal medulla of the rat. This immunoreactivity was found to be associated with the chromaffin granule. This study is directed at isolating the messenger ribonucleic acid that encodes for preproinsulin. Reverse transcription coupled with polymerase chain reaction was used. Complementary deoxyribonucleic acid (cDNA) was amplified, extracted and reamplified. It was then subjected to digestion with four different restriction endonuclease enzymes. Its resemblance to the corresponding cDNA that encodes for preproinsulin I in the rat was established. Our results suggest that insulin is synthesized in the rat adrenal gland for autocrine, paracrine, neuromodulation or local physiologic function.

Adrenal Glands↗