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Biomedical subjects

A Thornton

Publications and source records attributed to A Thornton.

At least 109 records · Page 6Linked to original sources
PubMed1979

Fertility and income consumption aspirations, and child quality standards.

Data from a 1975 national survey of the American population were used to investigate the relationships between childbearing and aspirations for consumption goods, child quality standards, and income. The data were consistent with the hypothesis that preferences for child quality are negatively related to fertility. Aspirations for consumer goods which are related to the home were not found to be negatively related to childbearing while aspirations for nonhome goods were negatively related to fertility as hypothesized. Several indicators of income and subjective economic well-being were examined, and the overall pattern of results was not supportive of the hypothesized effect of income on fertility.

Adolescent↗
PubMed1979

Anomalous origin of the left anterior descending coronary artery from the pulmonary trunk.

An extremely rare congenital abnormality is reported in which the anterior descending branch of the left main coronary artery arises independently from the pulmonary trunk in a young patient who presented with unstable angina. Its clinical presentation, angiographic identification and surgical treatment are described. It appears to be a distinct entity with few of the features of the classical form of anomalous origin of the left main coronary artery.

Adult↗
PubMed1978

Hepatitis B outbreak among chimpanzees at the London Zoo.

Persistent carriage of hepatitis B virus in extremely high titre was identified in 5 out of 9 chimpanzees kept at the London Zoo. Antibody to this virus was present in the other 4 chimpanzees. Serological survey of the other primates in the Regent's Park collection did not reveal the presence of the surface antigen in 2 gorillas, 11 orang-utans, and 2 gibbons, although surface antibody was present in the serum of 1 gorilla and 2 orang-utans. 3 of the carrier chimpanzees were born at the Zoo and were the offspring of either a carrier mother or a carrier father, and perinatal transmission may have occurred. A strict safety code of practice was introduced and hepatitis B immunoglobulin was given at intervals to designated staff members. Sero-conversion did not occur in any of the 38 staff members under surveillance for more than 2 years. Treatment of the carrier state in the chimpanzees was attempted with human leucocyte interferon, with and without ribavirin ('Virazole'), and with adenine arabinoside, but the effects were mostly temporary.

Animals↗
PubMed1978

Marital dissolution, remarriage, and childbearing.

Earlier models of fertility hypothesize that marital dissolution and remarriage influence subsequent childbearing. This issue is examined by comparing the fertility of those in disrupted marriages with that of those in stable marriages. The results indicate that, by transferring women into a nonmarried status, marital dissolution decreases childbearing. The data also suggest that discord reduces fertility even before separation occurs--separated women had reduced fertility during the two years just before separation. It was found that marital dissolution without remarriage operates to truncate childbearing, thus decreasing family size. Dissolution followed by remarriage, however, lengthens the childbearing span of whites and has no inflences on average family size; remarrying white women are able to make up for the childbearing lost between marriages. For nonwhites, we found that dissolution and remarriage increase the average time to childbirth, but, even more importantly, these events greatly decrease the number of children born.

Adult↗
PubMedDate not supplied

Nurse managers in Australia: mentoring, leadership and career progression.

Identification of those leadership qualities which nurses believe led to their successful attainment of a nursing management position may help in understanding how to identify and foster leadership potential amongst nursing staff. This study asked nurse managers to indicate the important factors which influenced and facilitated their entry to management positions with a particular reference to the development of leadership characteristics. The results suggest that the leadership qualities we expect nurse managers to display evolve in a largely random way. Additionally, there is evidence that the development of leadership skills and attainment of management positions remains fragmented and random in nature. Because of this, individual nurse managers develop leadership skills almost by default using informal strategies to learn and develop. These findings should provide direction to educational providers and senior managers who seek to develop future leaders and managers.

Attitude of Health Personnel↗
PubMedDate not supplied

Luminal epithelial antigen (LEA.135) expression in adenocarcinoma of the colon.

BACKGROUND: Luminal Epithelial Antigen (LEA.135) is a cell surface glycoprotein, whose expression has been shown to have prognostic significance in breast carcinoma and transitional cell carcinoma of the bladder, but has not been previously evaluated in adenocarcinoma of the colon. PATIENTS AND METHODS: This study examines LEA.135 expression in 134 archival cases of colon adenocarcinoma obtained from Wellington Hospital Pathology Department between 1985 and 1990 inclusive. The findings were compared with tumor grade, stage and survival, to determine whether LEA.135 could serve as a useful indicator of the progression of colonic adenocarcinoma. RESULTS: Analysis of results showed that LEA.135 expression was not related to depth of invasion (p = 0.097), grade (p = 0.14) or clinical outcome (p = 0.27). Both luminal and cytoplasmic labelling of LEA.135 was seen in tumor cells however there was no association between LEA.135 distribution and either tumor grade or patient survival. CONCLUSION: The results suggest that the expression of LEA.135 does not provide a useful indication of clinical progression or outcome in patients with colonic adenocarcinoma.

Adenocarcinoma↗
PubMedDate not supplied

Oral shark cartilage does not abolish carcinogenesis but delays tumor progression in a murine model.

BACKGROUND: Shark cartilage and shark cartilage extracts have been reported to have anti-angiogenic and anti-neoplastic properties. This study reports the effects of oral administration of powdered shark cartilage on tumor progression in a murine renal tumor model. MATERIALS AND METHODS: Renal tumors were induced in CBA female mice by a single bolus of IV streptozotocin. 57 mice were fed shark cartilage and the numbers and rate of development of dysplastic convoluted tubules, papillary and solid renal epithelial tumors was compared with 57 control mice over an 88 week follow-up period. RESULTS: In the shark cartilage fed group dysplasia was first observed after 23 weeks (control 19 weeks), papillary tumors after 24 weeks (control 23 weeks) and solid tumors after 55 weeks (control 19 weeks). There was no significant difference in the rate of development of dysplastic tubules between test and control animals. The development of papillary and solid tumors was significantly delayed in the test group. CONCLUSIONS: In this tumor model oral shark cartilage delays, but does not abolish, tumor progression.

Administration, Oral↗
PubMedDate not supplied

The long-term impact of pregnancy at marriage on the family's economic circumstances.

In the long run, premaritally pregnant white couples seem able to overcome the problems stemming from early marriage and parenthood. They earn middle-class incomes, own their homes, have some savings. But they do have 22 percent less in total assets and they have more unplanned children than couples who married and deferred childbearing.

Adult↗