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A Toth

Publications and source records attributed to A Toth.

68 records · Page 4Linked to original sources
PubMedDate not supplied

Asymptomatic bacteriospermia in infertile men.

The aerobic and anaerobic flora of the semen was examined in 109 men visiting our infertility clinic. Not one specimen was sterile and 107 specimens contained two or more different bacterial species. Anaerobic organisms were found in 63.3% of specimens. We were able to isolate various organisms that have been shown to be spermicidal in vitro (viridans and hemolytic streptococci, Proteus vulgaris and Escherichia coli) from a large number of samples. If the presence of microorganisms in the semen is associated with infertility, it is likely that only certain organisms are involved or that the numbers of organisms must be high for an effect to be seen. The presence of organisms in the semen may also be related to gynecologic infections.

Adult↗
PubMedDate not supplied

Effect of doxycycline on pre-menstrual syndrome: a double-blind randomized clinical trial.

Thirty patients with well-defined symptoms of pre-menstrual syndrome were randomly treated with the antibiotic doxycycline or placebo. The antibiotic-treated group showed a highly significant reduction of symptoms. Subsequent antibiotic treatment of the original placebo group similarly diminished the symptoms in this group. A 6-month follow-up demonstrated that the improvement in symptom scores was permanent and independent from the presence of the antibiotic. Luteal phase endometrial biopsies showed a high incidence of out-of-phase endometrium. An unexpectedly high percentage of endometrial biopsy cultures yielded positive findings for mycoplasma, Chlamydia trachomatis and anaerobic bacteria. There were no characteristic hormonal changes in this study group. An infectious aetiology, possibly a sub-clinical endometrial or ovarian infection, behind certain cases of pre-menstrual syndrome is postulated.

Adult↗